Secondary progressive multiple sclerosis: current knowledge and future challenges

M Rovaris, C Confavreux, R Furlan, L Kappos… - The Lancet …, 2006 - thelancet.com
m without rest), score 6 (walking with unilateral support and a walking distance not exceeding
100 m … onto a wall or furniture but not exceeding 10 m without rest). In this cohort, the …

Diffusion MRI in multiple sclerosis

M Rovaris, A Gass, R Bammer, SJ Hickman… - Neurology, 2005 - AAN Enterprises
Diffusion imaging is a quantitative, MR-based technique potentially useful for the study of
multiple sclerosis (MS), due to its increased pathologic specificity over conventional MRI and …

MRI and the diagnosis of multiple sclerosis: expanding the concept of “no better explanation”

A Charil, TA Yousry, M Rovaris, F Barkhof… - The Lancet …, 2006 - thelancet.com
Although the diagnosis of multiple sclerosis relies on the demonstration of disease dissemination
in space and time, the exclusion of other neurological disorders is also essential. The …

Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study

…, HP Hartung, P Seeldrayers, PS Sørensen, M Rovaris… - The Lancet, 2001 - thelancet.com
Background Interferon beta reduces activity in multiple sclerosis as measured clinically and
by magnetic resonance imaging (MRI). We assessed the effect of interferon beta-1a on the …

Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis

…, MD Cava, M Onofrj, M Rovaris, M Salvetti… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people …

Central nervous system sarcoidosis—diagnosis and management

JP Zajicek, NJ Scolding, O Foster, M Rovaris… - Qjm, 1999 - academic.oup.com
A series of 68 patients with neurosarcoidosis is reported, with particular emphasis on clinical
aspects, diagnosis and treatment. A classification system based on clinical diagnostic …

Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis

M Filippi, M Bozzali, M Rovaris, O Gonen, C Kesavadas… - Brain, 2003 - academic.oup.com
Although axonal pathology is recognized as one of the major pathological features of multiple
sclerosis, it is less clear how early in its course it occurs and how it correlates with MRI‐…

Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes

N De Stefano, A Giorgio, M Battaglini, M Rovaris… - Neurology, 2010 - AAN Enterprises
Objective: To assess the time course of brain atrophy and the difference across clinical
subtypes in multiple sclerosis (MS). Methods: The percent brain volume change (PBVC) was …

MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study

…, KA Miszkiel, GT Plant, C Polman, M Rovaris… - The Lancet …, 2007 - thelancet.com
Background The 2001 and 2005 McDonald criteria allow MRI evidence for dissemination in
space (DIS) and dissemination in time (DIT) to be used to diagnose multiple sclerosis in …

MRI criteria for MS in patients with clinically isolated syndromes

…, L Kappos, J Palace, C Polman, M Rovaris… - Neurology, 2010 - AAN Enterprises
In recent years, criteria for the diagnosis of multiple sclerosis (MS) have changed, mainly
due to the incorporation of new MRI criteria. While the new criteria are a logical step forward, …