Neuropathic pain is a common and severely disabling state that affects millions of people
worldwide. Such pain can be experienced after nerve injury or as part of diseases that affect …

Acute nociceptive pain is a key defence system that enables the detection of danger signals
that threaten homeostasis and survival. However, chronic pain (such as the neuropathic …

… Furthermore, mice lacking P2X 4 R fail to develop tactile allodynia after nerve injury (Tsuda
and Inoue, unpublished observations). Moreover, spinal administration of P2X 4 R-…

The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern 1
. In this study, our statistical modelling suggests that Omicron has spread more rapidly than …

… f, Mean ± sem peak current evoked by GABA measured in LI neurons at various values of
V m in slices taken from the rats in d. Horizontal standard error bars represent interneuron …

During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (…

Pain after nerve damage is an expression of pathological operation of the nervous system 1
, 2 , one hallmark of which is tactile allodynia—pain hypersensitivity evoked by innocuous …

Background Patients with advanced gastric or gastro-oesophageal junction cancer refractory
to, or intolerant of, two or more previous regimens of chemotherapy have a poor prognosis, …

In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified, and XBB is
spreading rapidly around the world. Our phylogenetic analyses suggested that XBB …

… ) or triplicate (E–G, I, J, K, and M), and the presented data are expressed as the average ±
SD. … Sera were inactivated at 56 C for 30 m and stored at –80 C until use. The details of the …