The factor that is most relevant and strongly associated with the clinical course of multiple
sclerosis is chronological age. Very young patients exclusively have relapsing remitting …

The neuropathological and biological understanding of disease progression in multiple
sclerosis have progressed in the last few years. As a consequence, new therapeutic approaches …

Over the past few decades, MRI-based visualization of demyelinated CNS lesions has
become pivotal to the diagnosis and monitoring of multiple sclerosis (MS). In this Review, we …

Multiple sclerosis (MS) lesions that do not resolve in the months after they form harbour
ongoing demyelination and axon degeneration, and are identifiable in vivo by their …

10.7554/eLife.29738.001 Here, we report the existence of meningeal lymphatic vessels in
human and nonhuman primates (common marmoset monkeys) and the feasibility of …

Objective: This study explores default-mode network (DMN) abnormalities in patients with
secondary progressive (SP) and primary progressive (PP) multiple sclerosis (MS) and whether …

Importance In multiple sclerosis (MS), chronic active lesions, which previously could only be
detected at autopsy, can now be identified on susceptibility-based magnetic resonance …

A new semi-automatic method for segmenting the spinal cord from MR images is presented.
The method is based on an active surface (AS) model of the cord surface, with intrinsic …

… Absinta M, Nair G, Filippi M, et al. Postmortem magnetic resonance imaging to guide the …
Reich, Martina Absinta, and Luisa Vuolo contributed to study concept and design. Daniel S. …

… An experienced neuroradiologist (DS Reich) read all the scans clinically, and a neurologist
with experience in MS imaging (M. Absinta) analyzed the data. DCE and phase post-…