User profiles for M. Jain

mukesh jain

- Verified email at case.edu - Cited by 22976

Maneesh Jain

- Verified email at unmc.edu - Cited by 16312

Miten Jain

- Verified email at northeastern.edu - Cited by 11580

[HTML][HTML] Nanopore sequencing and assembly of a human genome with ultra-long reads

M Jain, S Koren, KH Miga, J Quick, AC Rand… - Nature …, 2018 - nature.com
We report the sequencing and assembly of a reference genome for the human GM12878
Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore sequencer. …

Tumour exosome integrins determine organotropic metastasis

…, MA Hollingsworth, M De Sousa, S Kaur, M Jain… - Nature, 2015 - nature.com
Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one
of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human …

[BOOK][B] Numerical methods for scientific and engineering computation

MK Jain - 2003 - books.google.com
We We thank the faculty and the students for sending their suggestions for improving this
book. Based on these suggestions, we have made a number of changes in the text and have …

Targeting the EGFR signaling pathway in cancer therapy

…, MP Ponnusamy, D Haridas, M Jain… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Cancer is a devastating disease; however, several therapeutic advances have
recently been made, wherein EGFR and its family members have emerged as useful …

Should immunonutrition become routine in critically ill patients?: A systematic review of the evidence

DK Heyland, F Novak, JW Drover, M Jain, X Su… - Jama, 2001 - jamanetwork.com
… Digiovine B, Chenoweth C, Watts C, Higgins M. The attributable mortality and costs of …
Digiovine B, Chenoweth C, Watts C, Higgins M. The attributable mortality and costs of primary …

Anti-inflammatory effects of statins: clinical evidence and basic mechanisms

MK Jain, PM Ridker - Nature reviews Drug discovery, 2005 - nature.com
Chronic inflammation is a key feature of vascular disease states such as atherosclerosis.
Multiple clinical studies have shown that a class of medications termed statins lower …

The complete sequence of a human genome

…, M Haukness, K Howe, MW Hunkapiller, C Jain, M Jain… - Science, 2022 - science.org
Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. …

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

…, PM Grandgenett, MA Hollingsworth, M Jain… - Nature cell …, 2015 - nature.com
Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis, mainly
due to delayed detection. We hypothesized that intercellular communication is critical for …

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo …

…, C Iastrebner, O Ioachimescu, M Jain… - The lancet Respiratory …, 2021 - thelancet.com
Background Baricitinib is an oral selective Janus kinase 1/2 inhibitor with known anti-inflammatory
properties. This study evaluates the efficacy and safety of baricitinib in combination …

[HTML][HTML] Baricitinib plus remdesivir for hospitalized adults with Covid-19

…, N Erdmann, N Ahuja, M Frank, M Oh… - … England Journal of …, 2021 - Mass Medical Soc
Background Severe coronavirus disease 2019 (Covid-19) is associated with dysregulated
inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, …