Carcinogenesis is a mechanistically complex and variable process with a plethora of
underlying genetic causes. Cancer development comprises a multitude of steps that occur …

The complex process of apoptosis is orchestrated by caspases, a family of cysteine
proteases with unique substrate specificities. Accumulating evidence suggests that cell death …

Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a
neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK-ERK) …

The Coulomb excitation of a very neutron-rich nucleus 32 Mg to its 2 + state was studied using
an unstable nuclear beam of 32 Mg at 49.2 MeV/u with a 208 Pb target. The B(E2) value …

We tested the hypothesis that “good feelings”—the central element of subjective well-being—are
associated with interdependence and interpersonal engagement of the self in Japan, …

… For a given sample ζ, the averaged best-fit m references, S i,m REF , is calculated as 1 / m(∑
j 2 cΛj,ζ × S i ζ ), where j (1, 2,…, m) represents the m reference samples in which the SD of …

… Author Contributions M.Ka., KN and MS performed microarray experiments and
subsequent data analyses. … Kumi Nakazaki & Mineo Kurokawa … Mineo Kurokawa …

Embryonic development of multilineage hematopoiesis requires the precisely regulated
expression of lineage-specific transcription factors, including AML-1 (encoded by Runx1; also …

Evaluating Nilotinib Efficacy and Safety in Clinical Trials Newly Diagnosed Patients
compares nilotinib and imatinib in patients with newly diagnosed chronic myeloid leukemia in …

… Author Contributions MS and M.Kato performed microarray experiments and … YS, MS, M.Kato,
KN, JT and AT performed mutation analysis. HO performed pathological … Mineo Kurokawa …