Medulloblastoma is the most common malignant brain tumor of childhood. While prognosis
has significantly improved in the last decades with multimodal therapy including surgery, …

Patients after solid organ transplantation (SOT) carry a substantially increased risk to develop
malignant lymphomas. This is in part due to the immunosuppression required to maintain …

Medulloblastoma is a highly malignant paediatric brain tumour currently treated with a
combination of surgery, radiation and chemotherapy, posing a considerable burden of toxicity to …

Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and
children. They represent a morphologically heterogeneous class of tumours and some entities …

The large diversity of central nervous system (CNS) tumor types in children and adolescents
results in disparate patient outcomes and renders accurate diagnosis challenging. In this …

In 2012, an international consensus paper reported that medulloblastoma comprises four
molecular subgroups (WNT, SHH, Group 3, and Group 4), each associated with distinct …

In recent years, tools for early detection of irreversible trauma to the basilar membrane during
hearing preservation cochlear implant (CI) surgery were established in several clinics. A …

Purpose Posterior fossa ependymoma comprises two distinct molecular variants termed
EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic value …

This study aimed to prospectively evaluate clinical, histopathological and molecular
variables for outcome prediction in medulloblastoma patients. Patients from the HIT2000 …

English Purpose To assess an intensified treatment in the context of clinical and biologic
risk factors in metastatic medulloblastoma. Patients and Methods Patients (4 to 21 years old, …