Quantitative MRI in multiple sclerosis: from theory to application

M Tranfa, G Pontillo, M Petracca… - American Journal …, 2022 - Am Soc Neuroradiology
Quantitative MR imaging techniques allow evaluating different aspects of brain microstructure,
providing meaningful information about the pathophysiology of damage in CNS disorders. …

A Review of Brain and Pituitary Gland MRI Findings in Patients with Ataxia and Hypogonadism

A Scaravilli, M Tranfa, G Pontillo, B Brais, G De Michele… - The cerebellum, 2024 - Springer
The association of cerebellar ataxia and hypogonadism occurs in a heterogeneous group of
disorders, caused by different genetic mutations often associated with a recessive …

Ataxia and Hypogonadism: a Review of the Associated Genes and Syndromes

G De Michele, L Maione, S Cocozza, M Tranfa, C Pane… - The Cerebellum, 2023 - Springer
The association of hypogonadism and cerebellar ataxia was first recognized in 1908 by
Gordon Holmes. Since the seminal description, several heterogeneous phenotypes have been …

MR imaging signs of gadolinium retention are not associated with long-term motor and cognitive outcomes in multiple sclerosis

A Scaravilli, M Tranfa, G Pontillo… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The long-term impact of gadolinium retention in the dentate
nuclei of patients undergoing administration of seriate gadolinium-based contrast agents …

The central vein sign helps in differentiating multiple sclerosis from its mimickers: lessons from Fabry disease

M Tranfa, M Tortora, G Pontillo, V Iuzzolino, E Riccio… - European …, 2022 - Springer
… In this retrospective study, we evaluated brain MRI exams of 57 FD (M/F = 26/31; mean
age: 42.1 ± 10.2) and 73 MS patients (M/F = 8/65; mean age: 38.6 ± 11.2) acquired between …

[HTML][HTML] CHARON: An Imaging-Based Diagnostic Algorithm to Navigate Through the Sea of Hereditary Degenerative Ataxias

A Scaravilli, M Tranfa, G Pontillo, B Brais, G De Michele… - The Cerebellum, 2024 - Springer
The complexity in diagnosing hereditary degenerative ataxias lies not only in their rarity, but
also in the variety of different genetic conditions that can determine sometimes similar and …

A polynomial regression-based approach to estimate relaxation rate maps suitable for multiparametric segmentation of clinical brain MRI studies in multiple sclerosis

MA Pirozzi, M Tranfa, M Tortora, R Lanzillo… - Computer Methods and …, 2022 - Elsevier
Background and Objective Relaxation parameter maps (RPMs) calculated from spin-echo
data have provided a basis for the segmentation of normal brain tissues and white matter …

[HTML][HTML] Tongue Mucoceles: a retrospective clinic-pathological evaluation of 240 cases

R Patini, M Giuliani, G Gioco, M Tranfa, VCA Caponio… - BMC Oral Health, 2023 - Springer
Background Minor salivary glands can be found in the ventral and anterior part of the tongue;
these glands can rarely develop mucoceles that, due to their rarity and their unusual …

The impact of image contrast, resolution and reader expertise on black hole identification in Multiple Sclerosis

M Tranfa, A Scaravilli, C Pastore, A Montella, R Lanzillo… - Neuroradiology, 2024 - Springer
Objectives In the neuroradiological work-up of Multiple Sclerosis (MS), the detection of “black
holes” (BH) represent an information of undeniable importance. Nevertheless, different …

[HTML][HTML] Clinical Evaluation of the Optical Filter for Autofluorescence Glasses for Oral Cancer Curing Light Exposed (GOCCLES®) in the Management of Potentially …

C Lajolo, M Tranfa, R Patini, A Fiorino… - International Journal of …, 2022 - mdpi.com
Background: Any oral potentially malignant disorders (OPMDs) must be regularly monitored
through clinical examination to detect any possible malignant transformation. Conventional …