‘Reactive oxygen species’ (ROS) is a generic term that defines a wide variety of oxidant
molecules with vastly different properties and biological functions that range from signalling to …

IgG4-related disease is a newly recognized fibro-inflammatory condition characterized by
several features: a tendency to form tumefactive lesions in multiple sites; a characteristic …

IgG4-related disease (IgG4-RD) is an immunemediated fibroinflammatory condition that can
affect multiple organs and lead to tumefactive, tissuedestructive lesions and organ failure (1)…

Stimulation of Toll-like receptors (TLRs) triggers activation of a common MyD88-dependent
signaling pathway as well as a MyD88-independent pathway that is unique to TLR3 and …

Toll-like receptors (TLRs) recognize microbial components and trigger the inflammatory and
immune responses against pathogens. IκBζ (also known as MAIL and INAP) is an ankyrin-…

To estimate the minimal gene set required to sustain bacterial life in nutritious conditions, we
carried out a systematic inactivation of Bacillus subtilis genes. Among ≈4,100 genes of the …

Heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors (GPCRs)
respond to a variety of different external stimuli and activate G proteins. GPCRs share many …

… researchers concerns the annotation or identification of m/z features in MS spectra obtained
from metabolomics studies. In many cases, the number of m/z features in untargeted MS-…

Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non-European …

The innate immune system senses viral infection by recognizing a variety of viral
components (including double-stranded (ds)RNA) and triggers antiviral responses 1 , 2 . The …