The biochemistry of amyloid proteins has been a fascinating and important area of research
because of its contribution to our understanding of protein folding dynamics and assembly …

Background: Patients with multiple sclerosis (MS) and clinically isolated syndrome (CIS) may
show alterations of retinal layer architecture as measured by optical coherence tomography…

Objective To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a large
cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected …

… Dr Hoshi reports receiving grants from Bayer Health Care and personal fees from Novartis
and Biogen Idec. Dr Mühlau reports receiving grants from Merck and Novartis. Dr Bellmann-…

Background Administration of a gadolinium-based contrast material is widely considered
obligatory for follow-up imaging of patients with multiple sclerosis (MS). However, advances in …

Objective To assess clinical characteristics, distribution of disease-modifying treatments (DMTs),
and neuropsychological symptoms in a large cohort of patients with early-stage MS. …

Background: Despite agreement about spinal cord atrophy in progressive forms of multiple
sclerosis (MS), data on clinically isolated syndrome (CIS) and relapsing–remitting MS (RRMS…

Background Antibodies to the aquaporin-4 (AQP4) water channel in neuromyelitis optica
spectrum disorder (NMOSD) are reported to trigger the complement cascade, which is …

Background: Damage of different brain structures has been related to fatigue. Alternatively,
functional alterations of central nervous system (CNS) cells by the inflammatory milieu within …

Importance Biomarkers to estimate long-term outcomes in patients with multiple sclerosis (MS)
and to assign patients to individual treatment regimens are urgently needed. Objective To …