User profiles for M.D. Jhaveri
Miral D JhaveriRush University Medical Center Verified email at rush.edu Cited by 1380 |
Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain
MD Jhaveri, D Richardson… - British journal of …, 2007 - Wiley Online Library
Cannabinoid CB 1 and CB 2 receptors are located at key sites involved in the relaying and
processing of noxious inputs. Both CB 1 and CB 2 receptor agonists have analgesic effects in …
processing of noxious inputs. Both CB 1 and CB 2 receptor agonists have analgesic effects in …
Cannabinoid CB2 Receptor-Mediated Anti-nociception in Models of Acute and Chronic Pain
MD Jhaveri, DR Sagar, SJR Elmes, DA Kendall… - Molecular …, 2007 - Springer
The endocannabinoid system consists of cannabinoid CB 1 and CB 2 receptors, endogenous
ligands and their synthesising/metabolising enzymes. Cannabinoid receptors are present …
ligands and their synthesising/metabolising enzymes. Cannabinoid receptors are present …
Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of …
SJR Elmes, MD Jhaveri, D Smart… - European Journal of …, 2004 - Wiley Online Library
Peripheral cannabinoid 2 receptors (CB 2 receptors) modulate immune responses and
attenuate nociceptive behaviour in models of acute and persistent pain. The aim of the present …
attenuate nociceptive behaviour in models of acute and persistent pain. The aim of the present …
Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats
DP Finn, MD Jhaveri, SRG Beckett, CH Roe… - …, 2003 - Elsevier
The analgesic potential of cannabinoids may be hampered by their ability to produce
aversive emotion when administered systemically. We investigated the hypothesis that the …
aversive emotion when administered systemically. We investigated the hypothesis that the …
Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain
MD Jhaveri, D Richardson, DA Kendall… - Journal of …, 2006 - Soc Neuroscience
Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation
of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is …
of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is …
Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome …
MD Jhaveri, D Richardson, I Robinson, MJ Garle… - …, 2008 - Elsevier
The antinociceptive effects of the endocannabinoids (ECs) are enhanced by inhibiting catabolic
enzymes such as fatty acid amide hydrolase (FAAH). The physiological relevance of the …
enzymes such as fatty acid amide hydrolase (FAAH). The physiological relevance of the …
Evidence for a novel functional role of cannabinoid CB2 receptors in the thalamus of neuropathic rats
MD Jhaveri, SJR Elmes, D Richardson… - European Journal of …, 2008 - Wiley Online Library
Cannabinoid CB 1 receptors have analgesic effects in models of neuropathic pain, but can
also produce psychoactive side‐effects. A supraspinal location of CB 2 receptors has recently …
also produce psychoactive side‐effects. A supraspinal location of CB 2 receptors has recently …
The utility of quantitative magnetic resonance angiography in the assessment of intracranial in-stent stenosis
S Prabhakaran, L Warrior, KR Wells, MD Jhaveri… - Stroke, 2009 - Am Heart Assoc
Background and Purpose— Noninvasive screening for intracranial in-stent stenosis is often
limited by artifact because of the stent or associated coils. We aimed to determine the utility …
limited by artifact because of the stent or associated coils. We aimed to determine the utility …
Inhibition of peripheral vanilloid TRPV1 receptors reduces noxious heat‐evoked responses of dorsal horn neurons in naïve, carrageenan‐inflamed and neuropathic …
MD Jhaveri, SJR Elmes, DA Kendall… - European Journal of …, 2005 - Wiley Online Library
The vanilloid TRPV1 receptor, present on primary afferent fibres, is activated by noxious
heat, low pH and endogenous vanilloids. Changes in the function or distribution of TRPV1 …
heat, low pH and endogenous vanilloids. Changes in the function or distribution of TRPV1 …
Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation
S Kelly, MD Jhaveri, DR Sagar… - European Journal of …, 2003 - Wiley Online Library
The presence of cannabinoid 1 (CB 1 ) receptors on primary afferent fibres may provide a
novel target for cannabinoid analgesics. The present study investigated the ability of …
novel target for cannabinoid analgesics. The present study investigated the ability of …