Diffusion tensor imaging of frontal lobe in autism spectrum disorder

SK Sundaram, A Kumar, MI Makki, ME Behen… - Cerebral …, 2008 - academic.oup.com
To investigate frontal lobe white matter in children with autism spectrum disorder (ASD), we
performed diffusion tensor imaging (DTI) in 50 ASD children (mean age: 57.5 ± 29.2 months, …

Alterations in frontal lobe tracts and corpus callosum in young children with autism spectrum disorder

…, L Sivaswamy, ME Behen, MI Makki… - Cerebral …, 2010 - academic.oup.com
… Because the scans for children with ASD or DI were clinical MRI studies, sedation was used
as necessary by the sedation team at Children's Hospital of Michigan. None of the control …

Altered water diffusivity in cortical association tracts in children with early deprivation identified with tract-based spatial statistics (TBSS)

RM Govindan, ME Behen, E Helder, MI Makki… - Cerebral …, 2010 - academic.oup.com
… Participation involved 2 visits to the Children's Hospital of Michigan. On the first visit, all the
children enrolled in the study first underwent a neuropsychological evaluation and neurologic …

Microstructural abnormalities of striatum and thalamus in children with Tourette syndrome

MI Makki, M Behen, A Bhatt, B Wilson… - … : official journal of the …, 2008 - Wiley Online Library
We applied diffusion‐tensor MRI (DT‐MRI) to investigate directly the water diffusivity within
subcortical gray matter structures comprising the fronto‐striato‐thalamic (FST) circuit, which is …

Altered fronto-striato-thalamic connectivity in children with Tourette syndrome assessed with diffusion tensor MRI and probabilistic fiber tracking

MI Makki, R Munian Govindan… - Journal of Child …, 2009 - journals.sagepub.com
The aim of the study was to determine whether abnormal connectivity of the fronto-striato-thalamic
circuit underlies the morphological changes in subcortical structures of patients with …

Diffusion tensor analysis of temporal and extra-temporal lobe tracts in temporal lobe epilepsy

RM Govindan, MI Makki, SK Sundaram, C Juhász… - Epilepsy research, 2008 - Elsevier
OBJECTIVE: To determine whether the major temporal lobe white matter tracts in patients
with temporal lobe epilepsy manifest abnormal water diffusion properties. METHODS: …

Characteristics of abnormal diffusivity in normal-appearing white matter investigated with diffusion tensor MR imaging in tuberous sclerosis complex

MI Makki, DC Chugani, J Janisse… - American journal of …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although patients with tuberous sclerosis complex (TSC)
manifest various structural abnormalities, we hypothesized that white matter (WM) structures …

Diffusion tensor imaging study of the cortical origin and course of the corticospinal tract in healthy children

…, E Asano, SK Sundaram, MI Makki… - American journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Several studies have questioned the traditional belief that
the corticospinal tract (CST) arises exclusively from the precentral gyrus and passes through …

Absence of arcuate fasciculus in children with global developmental delay of unknown etiology: a diffusion tensor imaging study

SK Sundaram, L Sivaswamy, MI Makki, ME Behen… - The Journal of …, 2008 - Elsevier
OBJECTIVE: To investigate cortical association tracts using diffusion tensor imaging (DTI) in
children with global developmental delay of unknown etiology. STUDY DESIGN: We …

Abnormal water diffusivity in corticostriatal projections in children with Tourette syndrome

RM Govindan, MI Makki, BJ Wilson… - Human brain …, 2010 - Wiley Online Library
The fronto‐striato‐thalamic circuit has been implicated in the pathomechanism of Tourette
Syndrome (TS). To study white and gray matter comprehensively, we used a novel technique …