Traumatic brain injury often results in cognitive impairments that limit recovery. The underlying
pathophysiology of these impairments is uncertain, which restricts clinical assessment …

Parkinson’s disease (PD) is associated with increased iron levels in the substantia nigra (SNc).
This study evaluated whether the iron chelator, deferiprone, is well tolerated, able to …

Axonal injury is a key determinant of long-term outcomes after traumatic brain injury (TBI) but
has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify …

Survivors of a traumatic brain injury can deteriorate years later, developing brain atrophy
and dementia. Traumatic brain injury triggers chronic microglial activation, but it is unclear …

Traumatic brain injury leads to significant loss of brain volume, which continues into the
chronic stage. This can be sensitively measured using volumetric analysis of MRI. Here we: (i) …

In 21 consecutive patients, the authors analyzed changes in venous Doppler waveforms of
damped or diminished cardiac pulsatility and respiratory phasicity. Each patient was …

Objective Pituitary dysfunction is a recognized consequence of traumatic brain injury (TBI)
that causes cognitive, psychological, and metabolic impairment. Hormone replacement offers …

See Bigler (doi: 10.1093/aww277 ) for a scientific commentary on this article. Post-traumatic
amnesia is very common immediately after traumatic brain injury. It is characterized by a …

It is proposed that the acquisition and maintenance of fluent speech depend on the rapid
temporal integration of motor feedforward and polysensory (auditory and somatosensory) …

Traumatic brain injury often produces executive dysfunction. This characteristic cognitive
impairment often causes long-term problems with behaviour and personality. Frontal lobe …