Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats

J Chen, Y Li, L Wang, Z Zhang, D Lu, M Lu, M Chopp - Stroke, 2001 - Am Heart Assoc
Background and Purpose—We tested the hypothesis that intravenous infusion of bone marrow
derived–marrow stromal cells (MSCs) enter the brain and reduce neurological functional …

Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats

J Chen, PR Sanberg, Y Li, L Wang, M Lu, AE Willing… - Stroke, 2001 - Am Heart Assoc
Background and Purpose— Human umbilical cord blood cells (HUCBC) are rich in stem and
progenitor cells. In this study we tested whether intravenously infused HUCBC enter brain, …

Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats

…, Y Li, L Wang, YX Xu, SC Gautam, M Lu… - Circulation …, 2003 - Am Heart Assoc
We tested the hypothesis that intravenous infusion of human bone marrow stromal cells (hMSCs)
promotes vascular endothelial growth factor (VEGF) secretion, VEGF receptor 2 (…

Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation

…, XH Zhang, Y Li, L Wang, J Chen, D Lu, M Lu… - …, 2000 - journals.lww.com
We tested the hypothesis that transplantation of bone marrow stromal cells (MSCs) into the
spinal cord after a contusion injury promotes functional outcome. Rats (n= 31) were subjected …

Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat

…, X Chen, L Wang, D Lu, M Lu… - Journal of …, 2003 - Wiley Online Library
The present study investigates the induction of neurogenesis, reduction of apoptosis, and
promotion of basic fibroblast growth factor (bFGF) expression as possible mechanisms by …

How virtual are we? Measuring virtuality and understanding its impact in a global organization

KM Chudoba, E Wynn, M Lu… - Information systems …, 2005 - Wiley Online Library
Employees in global corporations are increasingly involved in ‘virtual teams’ on a regular
basis. Conflicting definitions of virtuality make it hard to measure such things as how much …

Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats

J Chen, Y Li, L Wang, M Lu, X Zhang… - Journal of the neurological …, 2001 - Elsevier
We tested the hypothesis that bone marrow stromal cells (MSCs) transplanted into the
ischemic boundary zone, survive, differentiate and improve functional recovery after middle …

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

…, Y Wang, L Wang, H Jiang, C Zhang, M Lu… - Annals of …, 2003 - Wiley Online Library
We demonstrate that the 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) reductase
inhibitors atorvastatin and simvastatin enhance functional outcome and induce brain …

A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates

…, P Cao, XP Yang, T Yu, M Lu… - Proceedings of the …, 2009 - National Acad Sciences
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates serum LDL cholesterol (LDL-C)
by interacting with the LDL receptor (LDLR) and is an attractive therapeutic target for …

[HTML][HTML] Effects of tissue plasminogen activator for acute ischemic stroke at one year

…, BC Tilley, LB Morgenstern, M Lu… - … England Journal of …, 1999 - Mass Medical Soc
Background In 1995, the two-part National Institute of Neurological Disorders and Stroke (NINDS)
Recombinant Tissue Plasminogen Activator Stroke Study found that patients who …