[HTML][HTML] Brain swelling and death in children with cerebral malaria

…, SD Kampondeni, C Valim, MJ Potchen… - … England Journal of …, 2015 - Mass Medical Soc
Background Case fatality rates among African children with cerebral malaria remain in the
range of 15 to 25%. The key pathogenetic processes and causes of death are unknown, but a …

A systematic review of neuroimaging for cerebral palsy

…, G Birbeck, MC DeLano, MJ Potchen… - Journal of child …, 2008 - journals.sagepub.com
The American Academy of Neurology now recommends that all cases of cerebral palsy of
unknown origin undergo neuroimaging. Controversy surrounds this recommendation because …

High-b-value diffusion-weighted MR imaging of adult brain: image contrast and apparent diffusion coefficient map features

…, TG Cooper, JE Siebert, MJ Potchen… - American Journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent improvements in MR gradient technology allow
significant increases in diffusion weighting without prohibitive signal-to-noise degradation. The …

Acute brain MRI findings in 120 Malawian children with cerebral malaria: new insights into an ancient disease

MJ Potchen, SD Kampondeni… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: There have been few neuroimaging studies of pediatric CM,
a common often fatal tropical condition. We undertook a prospective study of pediatric CM …

[PDF][PDF] Linking EPCR-binding PfEMP1 to brain swelling in pediatric cerebral malaria

…, SA Danziger, F Duffy, SD Kampondeni, MJ Potchen… - Cell host & …, 2017 - cell.com
Brain swelling is a major predictor of mortality in pediatric cerebral malaria (CM). However,
the mechanisms leading to swelling remain poorly defined. Here, we combined neuroimaging…

Measuring performance in chest radiography

EJ Potchen, TG Cooper, AE Sierra, GR Aben… - Radiology, 2000 - pubs.rsna.org
PURPOSE: To use a standardized set of chest radiographs to quantify interobserver
differences and to provide a basis for comparing the diagnostic performance of physicians. …

Neurodevelopmental impairments 1 year after cerebral malaria

…, MP McDermott, R Brim, S Mboma, MJ Potchen… - …, 2019 - publications.aap.org
METHODS: We conducted an exposure-control study of 85 survivors of CM and 100 age-matched
patients in a control group who were enrolled at hospital discharge and assessed …

[HTML][HTML] 1.5 Tesla magnetic resonance imaging to investigate potential etiologies of brain swelling in pediatric cerebral malaria

MJ Potchen, SD Kampondeni, KB Seydel… - The American journal …, 2018 - ncbi.nlm.nih.gov
The hallmark of pediatric cerebral malaria (CM) is sequestration of parasitized red blood
cells in the cerebral microvasculature. Malawi-based research using 0.35 Tesla (T) magnetic …

Neuroimaging findings in children with retinopathy-confirmed cerebral malaria

MJ Potchen, GL Birbeck, JK DeMarco… - European journal of …, 2010 - Elsevier
PURPOSE: To describe brain CT findings in retinopathy-confirmed, paediatric cerebral
malaria. MATERIALS AND METHODS: In this outcomes study of paediatric cerebral malaria, a …

[HTML][HTML] Lipid metabolites of the phospholipase A2 pathway and inflammatory cytokines are associated with brain volume in paediatric cerebral malaria

V Pappa, K Seydel, S Gupta, CM Feintuch, MJ Potchen… - Malaria journal, 2015 - Springer
Background Cerebral malaria (CM) remains a significant cause of morbidity and mortality in
children in sub-Saharan Africa. CM mortality has been associated with increased brain …