We reviewed case-control studies of diffusion tensor imaging (DTI) in patients with Alzheimer's
dementia (AD) and mild cognitive impairment (MCI), in order to establish the relative …

Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

White matter hyperintensities (WMH) are frequently divided into periventricular (PWMH) and
deep (DWMH), and the two classes have been associated with different cognitive, …

Neural connections, providing the substrate for functional networks, exist whether or not they
are functionally active at any given moment. However, it is not known to what extent brain …

The APOE ε4 allele is a risk factor for late-life pathological changes that is also associated
with anatomical and functional brain changes in middle-aged and elderly healthy subjects. …

… Data are median (IQR) for non-parametric data and mean (SD) for parametric data, and n/N
(%), where N is the total number of participants with available data. p-values from …

The identification of resting state networks (RSNs) and the quantification of their functional
connectivity in resting-state fMRI (rfMRI) are seriously hindered by the presence of artefacts, …

Studies of resting FMRI data increasingly concern estimation at the group level, ie of differences
in functional connectivity patterns between different subject groups and/or between data …

… , Charlotte L Allan academic clinical lecturer in old age psychiatry1, Vyara Valkanova
specialist registrar in old age psychiatry1, Enikő Zsoldos postdoctoral scientist1, Nicola Filippini …

The human dorsal frontal cortex has been associated with the most sophisticated aspects of
cognition, including those that are thought to be especially refined in humans. Here we used …