[HTML][HTML] Challenges in exosome isolation and analysis in health and disease
N Ludwig, TL Whiteside, TE Reichert - International journal of molecular …, 2019 - mdpi.com
A growing body of evidence emphasizes the important role exosomes in different physiological
and pathological conditions. Exosomes, virus-size extracellular vesicles (EVs), carry a …
and pathological conditions. Exosomes, virus-size extracellular vesicles (EVs), carry a …
Ustilago maydis effectors and their impact on virulence
Biotrophic fungal plant pathogens establish an intimate relationship with their host to support
the infection process. Central to this strategy is the secretion of a range of protein effectors …
the infection process. Central to this strategy is the secretion of a range of protein effectors …
Systemic inflammatory response syndrome after surgery: mechanisms and protection
A Margraf, N Ludwig, A Zarbock… - Anesthesia & …, 2020 - journals.lww.com
… In a mouse model, heat injury to the liver leads to extensive neutrophil infiltration
controlled by the DAMP N-formyl-methionyl-leucyl-phenylalanine (fMLP), the neutrophil-signaling …
controlled by the DAMP N-formyl-methionyl-leucyl-phenylalanine (fMLP), the neutrophil-signaling …
[HTML][HTML] Dysregulation of brain and choroid plexus cell types in severe COVID-19
…, M McNerney, D Channappa, I Cobos, N Ludwig… - Nature, 2021 - nature.com
… with COVID-19 (n = 6 control individuals (without viral infection); n = 7 patients with COVID-…
by RT–qPCR (n = 6 control individuals (without viral infection), n = 7 patients with COVID-19…
by RT–qPCR (n = 6 control individuals (without viral infection), n = 7 patients with COVID-19…
Distribution of miRNA expression across human tissues
We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
Oxytocin selectively improves empathic accuracy
Empathic accuracy was operationalized as the time-series correlation between a participant’s
ratings of a target’s affect and the target’s own ratings of his or her affect. We calculated a …
ratings of a target’s affect and the target’s own ratings of his or her affect. We calculated a …
[HTML][HTML] Transport of extracellular vesicles across the blood-brain barrier: brain pharmacokinetics and effects of inflammation
Extracellular vesicles can cross the blood–brain barrier (BBB), but little is known about
passage. Here, we used multiple-time regression analysis to examine the ability of 10 exosome …
passage. Here, we used multiple-time regression analysis to examine the ability of 10 exosome …
[PDF][PDF] Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors
…, B Ziegler, S Bausenwein, N Nourkami, N Ludwig… - Cancer cell, 2015 - cell.com
… Screening of a larger cohort of unselected Wilms tumors by Sanger sequencing of genomic
DNA (n = 188) or allele-specific PCR (n = 529) identified 17 cases with the Q177R mutation …
DNA (n = 188) or allele-specific PCR (n = 529) identified 17 cases with the Q177R mutation …
Effects of oxytocin on recollections of maternal care and closeness
Although the infant–caregiver attachment bond is critical to survival, little is known about the
biological mechanisms supporting attachment representations in humans. Oxytocin plays a …
biological mechanisms supporting attachment representations in humans. Oxytocin plays a …
The hemibiotrophic lifestyle of Colletotrichum species
Colletotrichum species infect several economically important crop plants. To establish a
compatible parasitic interaction, a specialized infection cell, the melanized appressorium, is …
compatible parasitic interaction, a specialized infection cell, the melanized appressorium, is …