The vulnerable carotid artery plaque: current imaging methods and new perspectives

N Nighoghossian, L Derex, P Douek - Stroke, 2005 - Am Heart Assoc
Background and Purpose— Atherosclerosis is a diffuse, chronic inflammatory disorder that
involves the vascular, metabolic, and immune systems and leads to plaque vulnerability. The …

Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data

…, K Miwa, CA Molina, KW Muir, N Nighoghossian… - The Lancet, 2020 - thelancet.com
Background Patients who have had a stroke with unknown time of onset have been previously
excluded from thrombolysis. We aimed to establish whether intravenous alteplase is safe …

Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update

L Derex, N Nighoghossian - Journal of Neurology, Neurosurgery & …, 2008 - jnnp.bmj.com
Intracerebral haemorrhage (ICH) still represents the most feared complication of thrombolysis.
Our aim was to review the literature regarding clinical, biological and imaging predictors …

International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome

…, D Timann, J Honnorat, N Nighoghossian… - Journal of the …, 1997 - Elsevier
Despite the involvement of cerebellar ataxia in a large variety of conditions and its frequent
association with other neurological symptoms, the quantification of the specific core of the …

[HTML][HTML] MRI-guided thrombolysis for stroke with unknown time of onset

…, R Lemmens, KW Muir, N Nighoghossian… - … England Journal of …, 2018 - Mass Medical Soc
Background Under current guidelines, intravenous thrombolysis is used to treat acute stroke
only if it can be ascertained that the time since the onset of symptoms was less than 4.5 …

Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke: a gradient-echo T2*-weighted brain MRI study

N Nighoghossian, M Hermier, P Adeleine… - Stroke, 2002 - Am Heart Assoc
Background and Purpose— T2*-weighted gradient-echo MRI is known to detect old microbleeds
(MBs), considered indicative of microangiopathy. MBs might be a potential risk factor for …

[HTML][HTML] A comparison of two LDL cholesterol targets after ischemic stroke

…, E Meseguer, N Nighoghossian… - … England Journal of …, 2020 - Mass Medical Soc
Background The use of intensive lipid-lowering therapy by means of statin medications is
recommended after transient ischemic attack (TIA) and ischemic stroke of atherosclerotic origin…

Altered awareness of voluntary action after damage to the parietal cortex

…, E Daprati, S Ciancia, P Giraux, N Nighoghossian… - Nature …, 2004 - nature.com
… Black line: ERP grand average for normal controls (N = 5); Colored lines: ERPs for each
parietal patient. (N= 4). Signal was averaged over beep-locked epochs (from -200 ms to +1000 …

Factors influencing early admission in a French stroke unit

L Derex, P Adeleine, N Nighoghossian, J Honnorat… - Stroke, 2002 - Am Heart Assoc
Background and Purpose— Intravenous tissue plasminogen activator improves outcome after
ischemic stroke when given within 3 hours of symptoms onset in carefully selected patients…

Contribution of susceptibility-weighted imaging to acute stroke assessment

M Hermier, N Nighoghossian - Stroke, 2004 - Am Heart Assoc
Background— Susceptibility-weighted (SW) MRI provides insight into the pathophysiology of
acute stroke. We report on the use of SW imaging (SWI) sequences in clinical practice and …