Background In the Total Body Hypothermia for Neonatal Encephalopathy Trial (TOBY),
newborns with asphyxial encephalopathy who received hypothermic therapy had improved …

The Developing Human Connectome Project (dHCP) seeks to create the first 4-dimensional
connectome of early life. Understanding this connectome in detail may provide insights into …

… After comparison with a set of randomized networks, normalized C and L metrics, C n o r
m and L n o r m were found to significantly decrease over the preterm period (n = 28; paired t …

… We noted no significant differences in lactate to N-acetyl aspartate ratio in the thalamus (geometric
mean ratio 1·09, 95% CI 0·90 to 1·32) or fractional anisotropy (mean difference −0·01, …

Purpose The goal of the Developing Human Connectome Project is to acquire MRI in 1000
neonates to create a dynamic map of human brain connectivity during early development. …

Thalamocortical connections are: essential for brain function, established early in development,
and significantly impaired following preterm birth. Impaired cognitive abilities in preterm …

In the rodent brain the hemodynamic response to a brief external stimulus changes
significantly during development. Analogous changes in human infants would complicate the …

Preterm infants are at high risk of neurodevelopmental impairment, which may be due to
altered development of brain connectivity. We aimed to (i) assess structural brain development …

Detailed morphometric analysis of the neonatal brain is required to characterise brain
development and define neuroimaging biomarkers related to impaired brain growth. Accurate …

… M , m ∈ ℝ N ). These represent any combination of N features describing cortical folding,
brain function (such as resting state networks), cortical architecture, or structural connectivity. …