User profiles for N. Uchida
Naoshige UchidaProfessor of Molecular and Cellular Biology, Harvard University Verified email at mcb.harvard.edu Cited by 16048 |
The biology of hematopoietic stem cells
SJ Morrison, N Uchida… - Annual review of cell and …, 1995 - annualreviews.org
36 MORRISON, UCHIDA & WEISSMAN more HSC. In mouse and human, HSC represent
up to 0.05% of cells in the bone marrow. HSC are almost entirely responsible for the …
up to 0.05% of cells in the bone marrow. HSC are almost entirely responsible for the …
Family Systems Theory, Attachment Theory, and Culture*
F Rothbaum, K Rosen, T Ujiie, N Uchida - Family process, 2002 - Wiley Online Library
Family systems theory and attachment theory have important similarities and complementarities.
Here we consider two areas in which the theories converge: (a) in family system …
Here we consider two areas in which the theories converge: (a) in family system …
Neural circuitry of reward prediction error
Dopamine neurons facilitate learning by calculating reward prediction error, or the difference
between expected and actual reward. Despite two decades of research, it remains unclear …
between expected and actual reward. Despite two decades of research, it remains unclear …
Direct isolation of human central nervous system stem cells
N Uchida, DW Buck, D He… - Proceedings of the …, 2000 - National Acad Sciences
… In addition, many of these cells in the RMS expressed the human specific marker N-CAM
(… Some of these cells expressed human N-CAM, indicating that they were committed to …
(… Some of these cells expressed human N-CAM, indicating that they were committed to …
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
…, T Miyamoto, B Lyons, K Ohshima, N Uchida… - Nature …, 2007 - nature.com
… -C–treated AML-engrafted mouse bone marrow (n = 3). Two sets of representative plots are
… (d) Cell cycle status of LS cells and non-stem fractions in AML-engrafted recipients (n = 5). A …
… (d) Cell cycle status of LS cells and non-stem fractions in AML-engrafted recipients (n = 5). A …
Neuron-type-specific signals for reward and punishment in the ventral tegmental area
Dopamine has a central role in motivation and reward. Dopaminergic neurons in the ventral
tegmental area (VTA) signal the discrepancy between expected and actual rewards (that is, …
tegmental area (VTA) signal the discrepancy between expected and actual rewards (that is, …
[PDF][PDF] Whole-brain mapping of direct inputs to midbrain dopamine neurons
… Furthermore, we have verified that the patterns of labeling are similar at 5 days (n = 3 mice,
VTA) and 9 days (n = 2 mice, VTA) after the injection of SADDG-GFP(EnvA) compared to the …
VTA) and 9 days (n = 2 mice, VTA) after the injection of SADDG-GFP(EnvA) compared to the …
Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex
…, MA Yenari, IL Weissman, N Uchida… - Proceedings of the …, 2004 - National Acad Sciences
We characterize the survival, migration, and differentiation of human neurospheres derived
from CNS stem cells transplanted into the ischemic cortex of rats 7 days after distal middle …
from CNS stem cells transplanted into the ischemic cortex of rats 7 days after distal middle …
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
…, N Saxena, AB Wilkens, S Mantri, N Uchida… - Nature, 2016 - nature.com
… (n = 4 different SCD patient donors). b, HBB-targeted SCD HSPCs were analysed for GFP
expression by flow cytometry (n = 4 … of three different HSPC donors (n = 3 different SCD patient …
expression by flow cytometry (n = 4 … of three different HSPC donors (n = 3 different SCD patient …
Odor maps in the mammalian olfactory bulb: domain organization and odorant structural features
N Uchida, YK Takahashi, M Tanifuji, K Mori - Nature neuroscience, 2000 - nature.com
… acids (n = 13 rats), aliphatic aldehydes (n = 13), alcohols (n = 7) and straight chain alkanes
(n = 7). … In all OBs examined (n = 10), we consistently observed this gradual shift of activated …
(n = 7). … In all OBs examined (n = 10), we consistently observed this gradual shift of activated …