ICAR: endoscopic skull‐base surgery

…, TH Schwartz, JA Eloy, ND Adappa… - International forum of …, 2019 - Wiley Online Library
Background Endoscopic skull‐base surgery (ESBS) is employed in the management of diverse
skull‐base pathologies. Paralleling the increased utilization of ESBS, the literature in this …

International consensus statement on allergy and rhinology: olfaction

…, EH Holbrook, JH Turner, ND Adappa… - International forum of …, 2022 - Wiley Online Library
Background The literature regarding clinical olfaction, olfactory loss, and olfactory dysfunction
has expanded rapidly over the past two decades, with an exponential rise in the past year. …

Odontogenic sinusitis: developments in diagnosis, microbiology, and treatment

…, EJ Granquist, ND Adappa - Current opinion in …, 2018 - journals.lww.com
Odontogenic sinusitis has distinct pathophysiology, diagnostic considerations, microbiology,
and treatment strategies whenever compared with chronic rhinosinusitis. Clinicians who …

[HTML][HTML] T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection

…, V Abraham, L Doghramji, ND Adappa… - The Journal of …, 2012 - Am Soc Clin Investig
Innate and adaptive defense mechanisms protect the respiratory system from attack by
microbes. Here, we present evidence that the bitter taste receptor T2R38 regulates the mucosal …

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

…, M Santi, PB Storm, JYK Lee, JN Palmer, ND Adappa… - Nature …, 2014 - nature.com
Craniopharyngiomas are epithelial tumors that typically arise in the suprasellar region of the
brain 1 . Patients experience substantial clinical sequelae from both extension of the tumors …

[HTML][HTML] Bitter and sweet taste receptors regulate human upper respiratory innate immunity

…, L Doghramji, G Xiong, ND Adappa… - The Journal of …, 2014 - Am Soc Clin Investig
Bitter taste receptors (T2Rs) in the human airway detect harmful compounds, including
secreted bacterial products. Here, using human primary sinonasal air-liquid interface cultures …

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes

…, J Huang, JN Palmer, ND Adappa… - Proceedings of the …, 2021 - National Acad Sciences
Coronaviruses are adept at evading host antiviral pathways induced by viral double-stranded
RNA, including interferon (IFN) signaling, oligoadenylate synthetase–ribonuclease L (OAS-…

[PDF][PDF] Integrated proteogenomic characterization across major histological types of pediatric brain cancer

…, S Leary, J Moon, VA Petyuk, J Nazarian, ND Adappa… - Cell, 2020 - cell.com
We report a comprehensive proteogenomics analysis, including whole-genome sequencing,
RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 …

The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery

ND Adappa, Z Zhang, JN Palmer… - International forum of …, 2014 - Wiley Online Library
The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring
sinus surgery - Adappa - 2014 - International Forum of Allergy & Rhinology - Wiley Online …

[HTML][HTML] Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes

JP Earl, ND Adappa, J Krol, AS Bhat, S Balashov… - Microbiome, 2018 - Springer
Background Pan-bacterial 16S rRNA microbiome surveys performed with massively parallel
DNA sequencing technologies have transformed community microbiological studies. …