The known genetic mutation causing Huntington's disease (HD) makes this disease an
important model to study links between gene and brain function. An autosomal dominant family …

Understanding the progression of neurological diseases is vital for accurate and early
diagnosis and treatment planning. We introduce a new characterization of disease progression, …

Huntington's disease (HD) is a hereditary neurodegenerative disorder for which biological
indicators of disease progression, or disease stage, would be especially important for …

TRACK‐HD is a multicentre longitudinal observational study investigating the use of clinical
assessments and 3‐Tesla magnetic resonance imaging as potential biomarkers for future …

Background Unbiased longitudinal studies are needed to understand the distributed
neurodegenerative changes of Huntington's disease (HD). They may also provide tools for …

BACKGROUND AND PURPOSE: Longitudinal MR imaging measures provide an opportunity
to track progression in HD before the emergence of clinical symptoms. This may prove …

Huntington's disease (HD) is an inherited neurodegenerative disorder that classically presents
with motor, cognitive and psychiatric symptoms. However, other abnormalities also occur …

Background The occipital lobe is an important visual processing region of the brain. Following
consistent findings of early neural changes in the occipital lobe in Huntington's Disease (…

The impact of Huntington's disease neuropathology on the structure of the cingulate is uncertain,
with evidence of both cortical enlargement and atrophy in this structure in early clinical …

Introduction Huntington's disease (HD) is associated with progressive loss of caudate and
white matter volume and integrity. Our aim was to systematically assess interactions between …