Survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus on human skin: importance of hand hygiene in coronavirus disease …

…, H Ikegaya, Y Naito, N Watanabe… - Clinical Infectious …, 2021 - academic.oup.com
Background The stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
on human skin remains unknown, considering the hazards of viral exposure to humans. …

[HTML][HTML] The β-secretase BACE1 in Alzheimer's disease

…, M Irizarry, B Albala, A Koyama, N Watanabe… - Biological …, 2021 - Elsevier
BACE1 (beta-site amyloid precursor protein cleaving enzyme 1) was initially cloned and
characterized in 1999. It is required for the generation of all monomeric forms of amyloid-β (Aβ), …

[HTML][HTML] Differences in environmental stability among SARS-CoV-2 variants of concern: both omicron BA. 1 and BA. 2 have higher stability

…, Y Itoh, H Ikegaya, H Miyazaki, N Watanabe… - Clinical Microbiology …, 2022 - Elsevier
Objectives The increased infectivity and transmissibility of SARS-CoV-2 variants of concern (VOCs)
could cause significant human and economic damage. Hence, understanding their …

Quantitative assessment of air trapping in chronic obstructive pulmonary disease using inspiratory and expiratory volumetric MDCT

…, K Yagihashi, M Hoshino, N Watanabe… - American Journal of …, 2008 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of our study was to determine the attenuation threshold value for
the detection and quantification of air trapping using paired inspiratory and expiratory …

[HTML][HTML] C-terminal fragment of presenilin is the molecular target of a dipeptidic γ-secretase-specific inhibitor DAPT (N-[N-(3, 5-difluorophenacetyl)-L-alanyl]-S …

…, Y Tominari, H Fuwa, Y Okamura, N Watanabe… - Journal of Biological …, 2006 - ASBMB
γ-Secretase is a multimeric membrane protein complex composed of presenilin (PS), nicastrin,
Aph-1 and, Pen-2 that is responsible for the intramembrane proteolysis of various type I …

[HTML][HTML] Genome-wide association study identified three major QTL for carcass weight including the PLAG1-CHCHD7 QTN for stature in Japanese Black cattle

S Nishimura, T Watanabe, K Mizoshita, K Tatsuda… - BMC genetics, 2012 - Springer
Background Significant quantitative trait loci (QTL) for carcass weight were previously mapped
on several chromosomes in Japanese Black half-sib families. Two QTL, CW-1 and CW-2, …

Regional changes in brain gray and white matter in patients with schizophrenia demonstrated with voxel-based analysis of MRI

…, Y Kawasaki, T Takahashi, M Matsui, N Watanabe… - Schizophrenia …, 2002 - Elsevier
This study examined regional structural changes in the whole brain in 45 medicated
patients with schizophrenia (23 males and 22 females), comparing with 42 age- and sex-matched …

[HTML][HTML] Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma

…, D Vaitkus, T Fukuda, N Watanabe… - The Journal of …, 1999 - Am Soc Clin Investig
Asthma, a family of airway disorders characterized by airway inflammation, has an
increasing incidence worldwide. Platelet-activating factor (PAF) may play a role in the …

[HTML][HTML] Conversion of an ultra-wide bandgap amorphous oxide insulator to a semiconductor

J Kim, T Sekiya, N Miyokawa, N Watanabe… - NPG Asia …, 2017 - nature.com
The variety of semiconductor materials has been extended in various directions, for example,
to very wide bandgap materials such as oxide semiconductors as well as to amorphous …

[HTML][HTML] Pen-2 is incorporated into the γ-secretase complex through binding to transmembrane domain 4 of presenilin 1

N Watanabe, T Tomita, C Sato, T Kitamura… - Journal of Biological …, 2005 - ASBMB
γ-Secretase is a multimeric membrane protein complex comprised of presenilin (PS),
nicastrin (Nct), Aph-1, and Pen-2. It is a member of an atypical class of aspartic proteases that …