α[C-11]Methyl-l-Tryptophan PET Maps Brain Serotonin Synthesis and Kynurenine Pathway Metabolism
DC Chugani, O Muzik - Journal of Cerebral Blood Flow & …, 2000 - journals.sagepub.com
α[C-11]Methyl-l-tryptophan (AMT) is an analog of tryptophan used with positron emission
tomography for the measurement of serotonin synthesis in humans. Several attempts have …
tomography for the measurement of serotonin synthesis in humans. Several attempts have …
Imaging proliferation in vivo with [F-18] FLT and positron emission tomography
…, JM Lawhorn-Crews, JE Obradovich, O Muzik… - Nature medicine, 1998 - nature.com
Positron emission tomography (PET) is now regularly used in the diagnosis and staging of
cancer. These uses and its ability to monitor treatment response would be aided by the …
cancer. These uses and its ability to monitor treatment response would be aided by the …
Quantitative interictal subdural EEG analyses in children with neocortical epilepsy
E Asano, O Muzik, A Shah, C Juhász, DC Chugani… - …, 2003 - Wiley Online Library
Purpose: We studied the relation between quantitative interictal subdural EEG data and visually
defined ictal subdural EEG findings in children with intractable neocortical epilepsy, and …
defined ictal subdural EEG findings in children with intractable neocortical epilepsy, and …
Local brain functional activity following early deprivation: a study of postinstitutionalized Romanian orphans
HT Chugani, ME Behen, O Muzik, C Juhász, F Nagy… - Neuroimage, 2001 - Elsevier
… are largely consistent with those reported by others (eg, O’Connor and Rutter, 2000).
Specifically, the “late-placed” group in the O’Connor study had a mean global cognitive index that …
Specifically, the “late-placed” group in the O’Connor study had a mean global cognitive index that …
Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children
DC Chugani, O Muzik, M Behen… - Annals of Neurology …, 1999 - Wiley Online Library
… may result in altered serotonin modulation of thalamocortical connectivity, thus possibly
explaining abnormal sensory perception reported in many autistic subjects (reviewed by O’Neill …
explaining abnormal sensory perception reported in many autistic subjects (reviewed by O’Neill …
Abnormal brain connectivity in children after early severe socioemotional deprivation: a diffusion tensor imaging study
…, HT Chugani, ME Behen, C Juhász, O Muzik… - …, 2006 - publications.aap.org
OBJECTIVES. We previously reported that children who were subjected to early socioemotional
deprivation in Romanian orphanages showed glucose hypometabolism in limbic and …
deprivation in Romanian orphanages showed glucose hypometabolism in limbic and …
[HTML][HTML] Neonatal brain resting-state functional connectivity imaging modalities
…, MS Hassanpour, F Wallois, O Muzik… - Photoacoustics, 2018 - Elsevier
Infancy is the most critical period in human brain development. Studies demonstrate that
subtle brain abnormalities during this state of life may greatly affect the developmental …
subtle brain abnormalities during this state of life may greatly affect the developmental …
Metabolic costs and evolutionary implications of human brain development
…, LI Grossman, L Lipovich, O Muzik… - Proceedings of the …, 2014 - National Acad Sciences
… upon the nitrous oxide (N 2 O) method, which quantifies brain … consumption like N 2 O, which
therefore underestimate total … the brain, measured using the N 2 O method (24), is stable at …
therefore underestimate total … the brain, measured using the N 2 O method (24), is stable at …
Altered serotonin synthesis in the dentatothalamocortical pathway in autistic boys
DC Chugani, O Muzik, R Rothermel… - Annals of Neurology …, 1997 - Wiley Online Library
Based on reports of increased platelet serotonin in 30 to 50% of autistic subjects, abnormal
serotonergic neurotransmission may be important in the pathogenesis of autism. However, …
serotonergic neurotransmission may be important in the pathogenesis of autism. However, …
Brain mapping of language and auditory perception in high-functioning autistic adults: a PET study
…, RD Rothermel, DC Chugani, O Muzik… - Journal of autism and …, 1999 - Springer
We examined the brain organization for language and auditory functions in five high-functioning
autistic and five normal adults, using [ 15 O]-water positron emission tomography (PET). …
autistic and five normal adults, using [ 15 O]-water positron emission tomography (PET). …