User profiles for Ona Wu

Ona Wu

Associate Professor Radiology, Harvard Medical School, MGH Athinoula A Martinos Center
Verified email at nmr.mgh.harvard.edu
Cited by 16647

Mechanisms of migraine aura revealed by functional MRI in human visual cortex

…, M Sanchez del Rio, O Wu… - Proceedings of the …, 2001 - National Acad Sciences
Cortical spreading depression (CSD) has been suggested to underlie migraine visual aura.
However, it has been challenging to test this hypothesis in human cerebral cortex. Using high…

Tracer arrival timing‐insensitive technique for estimating flow in MR perfusion‐weighted imaging using singular value decomposition with a block‐circulant …

O Wu, L Østergaard, RM Weisskoff… - … in Medicine: An …, 2003 - Wiley Online Library
Relative cerebral blood flow (CBF) and tissue mean transit time (MTT) estimates from bolus‐tracking
MR perfusion‐weighted imaging (PWI) have been shown to be sensitive to delay …

DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4· 5 h of symptom onset (PRE-FLAIR): a multicentre observational study

…, B Cheng, M Ebinger, Q Hao, T Tourdias, O Wu… - The Lancet …, 2011 - thelancet.com
Background Many patients with stroke are precluded from thrombolysis treatment because
the time from onset of their symptoms is unknown. We aimed to test whether a mismatch in …

Diffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury

…, N Shetty-Alva, Y Ozsunar, O Wu… - American Journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Multiple biomarkers are used to quantify the severity of
traumatic brain injury (TBI) and to predict outcome. Few are satisfactory. CT and conventional …

Human acute cerebral ischemia: detection of changes in water diffusion anisotropy by using MR imaging

AG Sorensen, O Wu, WA Copen, TL Davis… - Radiology, 1999 - pubs.rsna.org
PURPOSE: To (a) determine the optimal choice of a scalar metric of anisotropy and (b)
determine by means of magnetic resonance imaging if changes in diffusion anisotropy occurred …

Acute stroke imaging research roadmap

…, R Silbergleit, AG Sorensen, J Wardlaw, O Wu… - Stroke, 2008 - Am Heart Assoc
The recent “Advanced Neuroimaging for Acute Stroke Treatment” meeting on September 7
and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, …

Neuroanatomic connectivity of the human ascending arousal system critical to consciousness and its disorders

BL Edlow, E Takahashi, O Wu, T Benner… - … of Neuropathology & …, 2012 - academic.oup.com
The ascending reticular activating system (ARAS) mediates arousal, an essential component
of human consciousness. Lesions of the ARAS cause coma, the most severe disorder of …

Functional magnetic resonance imaging of reorganization in rat brain after stroke

…, JM Ren, JB Mandeville, O Wu… - Proceedings of the …, 2001 - National Acad Sciences
Functional recovery after stroke has been associated with brain plasticity; however, the exact
relationship is unknown. We performed behavioral tests, functional MRI, and histology in a …

Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance …

…, AB Singhal, JB Mandeville, O Wu… - Journal of …, 2003 - Soc Neuroscience
The pattern and role of brain plasticity in stroke recovery has been incompletely characterized.
Both ipsilesional and contralesional changes have been described, but it remains unclear …

Predicting tissue outcome in acute human cerebral ischemia using combined diffusion-and perfusion-weighted MR imaging

O Wu, WJ Koroshetz, L Østergaard, FS Buonanno… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Tissue signatures from acute MR imaging of the brain may be
able to categorize physiological status and thereby assist clinical decision making. We …