We have examined the size dependence of extravasation and interstitial localization of
polyethyleneglycol-coated liposomes (PEG-liposomes) in the solid tumor tissue by means of …

Purpose. The purpose of this study was to determine the usefulness of transferrin (TF)-pendant-type
polyethyleneglycol (PEG)-liposomes (TF-PEG-liposomes), in which TF was …

Peritoneal dissemination in gastric cancer is a common fatal clinical condition with few effective
therapies available. We studied the therapeutic effect of a tumor‐targeting drug delivery …

In terms of active targeting by immunoliposomes, two anatomical compartments are considerable
for targeting sites. One is located a readily accessible site in intravascular, and another …

A basic experiment of peripheral nerve regeneration using neuronal progenitor cells
embedded in collagen gel was performed in a rat sciatic nerve defect. First, when neuronal …

The successful treatment of cancer by boron neutron-capture therapy (BNCT) requires the
selective delivery of relatively high concentration of 10 B compounds to malignant tumor tissue…

The articular cartilage consists of resident chondrocytes embedded within the extracellular
matrix which contains several components such as collagen and hyaluronic acids (HA). …

The extravasation of liposomes of different sizes into solid tumors after iv injection was
visualized by in vivo fluorescence microscopy in mouse neuroblastoma C-1300-bearing mice. …

We studied the effects of transforming growth factor-β 1 (TGF-β 1) on the genetic expression
of procollagen type I and III and its effects on structural properties in the early stages of …

Ral-binding protein 1 (RalBP1) is a putative effector protein of Ral and exhibits a GTPase
activating activity for Rac and CDC42. To clarify the function of RalBP1, we isolated a novel …