PURPOSE To investigate the use of six cerebral measures as correlates for hippocampal
volumes and, therefore, to enable normalized absolute hippocampal volumes to be calculated …

Body sway and vibration perception in the lower limbs were measured in 32 normal
subjects and 25 patients with peripheral neuropathies; nerve conduction studies were also …

Background Transforming growth factor beta 1 (TGFβ 1 ) is strongly induced following brain
injury and polarises microglia to an anti-inflammatory phenotype. Augmentation of TGFβ 1 …

Background Brain inflammation plays a key role in neurological disease. Although much
research has been conducted investigating inflammatory events in animal models, potential …

Mesial temporal lobe epilepsy (MTLE) is a neurological disorder associated with spontaneous
recurrent complex partial seizures and hippocampal sclerosis. Although increased …

Discussion Wernicke's encephalopathy is due to a deficiency of thiamine (vitamin B-1), an
essential cofactor in various stages ofcarhohydrate metabolism.'Transketolase is a thiamine …

Microglia, the resident macrophages of the central nervous system play vital roles in brain
homeostasis through clearance of pathogenic material. Microglia are also implicated in …

Cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) is a recently
recognized neurodegenerative ganglionopathy. Prompted by the presence of symptomatic …

Neuroinflammation contributes to the pathogenesis of several neurological disorders and
pericytes are implicated in brain inflammatory processes. Cellular inflammatory responses are …

The human brain is a highly vascular organ in which the blood-brain barrier (BBB) tightly
regulates molecules entering the brain. Pericytes are an integral cell type of the BBB, regulating …