User profiles for P. Alcaide-Leon

Paula Alcaide Leon

Assistant professor of Medical imaging, University of Toronto
Verified email at uhn.ca
Cited by 750

Spinal cord atrophy in multiple sclerosis: a systematic review and meta‐analysis

C Casserly, EE Seyman, P AlcaideLeon… - Journal of …, 2018 - Wiley Online Library
Alcaide-Leon has received funding through an unrestricted educational grant from Sanofi-Genzyme.
None of the other authors have any disclosures to declare. The authors would like …

Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives

A Di Ieva, T Lam, P Alcaide-Leon, A Bharatha… - Journal of …, 2015 - thejns.org
Susceptibility weighted imaging (SWI) is a relatively new imaging technique. Its high
sensitivity to hemorrhagic components and ability to depict microvasculature by means of …

Meta-analysis of timing of endovascular aneurysm treatment in subarachnoid haemorrhage: inconsistent results of early treatment within 1 day

S Rawal, P Alcaide-Leon, RL Macdonald… - Journal of Neurology …, 2017 - jnnp.bmj.com
Background and purpose To systematically review and meta-analyse the data on impact of
timing of endovascular treatment in aneurysmal subarachnoid haemorrhage (SAH) to …

Integrated models incorporating radiologic and radiomic features predict meningioma grade, local failure, and overall survival

…, G Valdes, M Pekmezci, P Alcaide-Leon… - Neuro-Oncology …, 2019 - academic.oup.com
Background We investigated prognostic models based on clinical, radiologic, and radiomic
feature to preoperatively identify meningiomas at risk for poor outcomes. Methods …

Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging

…, AM Molinaro, TL Luks, P Alcaide-Leon… - Neuro …, 2022 - academic.oup.com
Background Diagnostic classification of diffuse gliomas now requires an assessment of
molecular features, often including IDH-mutation and 1p19q-codeletion status. Because genetic …

Differentiation of enhancing glioma and primary central nervous system lymphoma by texture-based machine learning

P Alcaide-Leon, P Dufort, AF Geraldo… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Accurate preoperative differentiation of primary central
nervous system lymphoma and enhancing glioma is essential to avoid unnecessary …

Pattern of recurrence of glioblastoma versus grade 4 IDH-mutant astrocytoma following chemoradiation: A retrospective matched-cohort analysis

…, S Das, C Coolens, P Alcaide-Leon… - … in Cancer Research …, 2022 - journals.sagepub.com
Background and Purpose: To quantitatively compare the recurrence patterns of
glioblastoma (isocitrate dehydrogenase-wild type) versus grade 4 isocitrate dehydrogenase-mutant …

Quantitative spinal cord MRI in radiologically isolated syndrome

P Alcaide-Leon, K Cybulsky, S Sankar… - Neurology …, 2018 - AAN Enterprises
P. Alcaide-Leon received research support from Novartis. K. Cybulsky and S. …
Conceptualization of the study: Jiwon Oh and Paula Alcaide-Leon. Pulse sequence design/implementation …

Natural history of lesions with the MR imaging appearance of multinodular and vacuolating neuronal tumor

R Alsufayan, P Alcaide-Leon, LN De Tilly, DM Mandell… - Neuroradiology, 2017 - Springer
Purpose Multinodular and vacuolating neuronal tumor (MVNT) have been recently added to
the WHO classification of CNS tumors and has not been extensively reported upon in the …

Comparison of sagittal FSE T2, STIR, and T1-weighted phase-sensitive inversion recovery in the detection of spinal cord lesions in MS at 3T

P Alcaide-Leon, A Pauranik… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Determining the diagnostic accuracy of different MR sequences
is essential to design MR imaging protocols. The purpose of the study was to compare …