Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

…, JF Démonet, V Garibotto, P Giannakopoulos… - The Lancet …, 2017 - thelancet.com
The diagnosis of Alzheimer's disease can be improved by the use of biological measures.
Biomarkers of functional impairment, neuronal loss, and protein deposition that can be …

[HTML][HTML] Body mass index in midlife and dementia: systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies

…, M Egger, MJ Prince, P Giannakopoulos… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction We conducted a meta-analysis of the conflicting epidemiologic evidence on the
association between midlife body mass index (BMI) and dementia. Methods We searched …

Early diagnosis of Alzheimer's disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts

…, J Escudero, FJ Fraga, P Giannakopoulos… - Clinical …, 2020 - Elsevier
Alzheimer’s disease (AD) is the most common neurodegenerative disease among the elderly
with a progressive decline in cognitive function significantly affecting quality of life. Both the …

Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease

P Giannakopoulos, FR Herrmann, T Bussière… - Neurology, 2003 - AAN Enterprises
… model including both NFT counts and amyloid volume, total NFT numbers remained strongly
associated with decreased Nissl only–stained neuron numbers in all areas studied (p < …

Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: a quantitative evaluation of a one-year autopsy population …

C Bouras, PR Hof, P Giannakopoulos, JP Michel… - Cerebral …, 1994 - academic.oup.com
… of disorientation and mild cognitive impairment (p < 0.001), and Alzheimer's disease was
further correlated with the involvement of layer III of the inferior temporal cortex (p < 0.005). …

[HTML][HTML] Evidence-based guidelines for mental, neurological, and substance use disorders in low-and middle-income countries: summary of WHO recommendations

…, C Drummond, M Freeman, P Giannakopoulos… - PLoS …, 2011 - journals.plos.org
… Unützer, P. Ventevogel, L. Vijayakumar, G. … Jacob KS, Sharan P, Mirza I, Garrido-Cumbrera
M, Seedat S, et al. (2007) Mental health systems in countries: where are we now? Lancet …

Distinction between perceptual and attentional processing in working memory tasks: a study of phase-locked and induced oscillatory brain dynamics

…, L Fazio-Costa, V Ibanez, P Giannakopoulos - Journal of cognitive …, 2007 - direct.mit.edu
Working memory involves the short-term storage and manipulation of information necessary
for cognitive performance, including comprehension, learning, reasoning and planning. …

Frontal theta event-related synchronization: comparison of directed attention and working memory load effects

…, L Fazio-Costa, P Giannakopoulos… - Journal of neural …, 2006 - Springer
Early studies showed that long-term encoding and retrieval of new information is associated
with modulation of the theta rhythm. More recently, changes in theta power amplitude over …

Pain in severe dementia: Self‐assessment or observational scales?

…, F Herrmann, P Giannakopoulos… - Journal of the …, 2006 - Wiley Online Library
… MMSE score, dementia type, presence of depression, and type of scale used as independent
variables revealed that MMSE score was the strongest predictor of comprehension rates (P

Lewy body densities in the entorhinal and anterior cingulate cortex predict cognitive deficits in Parkinson's disease

…, A Canuto, PR Hof, C Bouras, P Giannakopoulos - Acta …, 2003 - Springer
… LB densities in the anterior cingulate cortex could explain 25.2% of this variability (P<0.01),
whereas LB and SP densities in the temporal cortex only marginally predicted CDR scores (…