User profiles for P. Nuutila

Pirjo Nuutila

professor of metabolic research, University of Turku
Verified email at utu.fi
Cited by 36179

[HTML][HTML] Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

…, AH Giang, M Khandekar, KA Virtanen, P Nuutila… - Cell, 2012 - cell.com
Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against
hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: …

Organ-specific physiological responses to acute physical exercise and long-term training in humans

…, JC Hannukainen, DJ Duncker, P Nuutila… - …, 2014 - journals.physiology.org
Virtually all tissues in the human body rely on aerobic metabolism for energy production and
are therefore critically dependent on continuous supply of oxygen. Oxygen is provided by …

[HTML][HTML] Functional brown adipose tissue in healthy adults

…, NJ Savisto, S Enerbäck, P Nuutila - … England Journal of …, 2009 - Mass Medical Soc
<p id="p001">Using positron-emission tomography (PET), we found that cold-induced glucose
uptake was increased by a factor of 15 in paracervical and supraclavicular adipose tissue …

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the SLEEVEPASS …

…, P Peromaa-Haavisto, S Hurme, M Soinio, P Nuutila… - Jama, 2018 - jamanetwork.com
… There was no statistically significant difference in QOL between groups (P = .85) and no
treatment-related mortality. At 5 years the overall morbidity rate was 19% (n = 23) for sleeve …

[PDF][PDF] Different metabolic responses of human brown adipose tissue to activation by cold and insulin

J Orava, P Nuutila, ME Lidell, V Oikonen, T Noponen… - Cell metabolism, 2011 - cell.com
… versus 2.8 ± 0.7 μmol/100 g/min, p = 0.002), but these effects remained lower than in BAT
(p = 0.003 and p = 0.01, subcutaneous WAT and VAT, respectively). The subjects who lacked …

Evidence for two types of brown adipose tissue in humans

…, M Slawik, T Mussack, D Nilsson, T Romu, P Nuutila… - Nature medicine, 2013 - nature.com
… The global Kruskal-Wallis P values are shown above each graph. The P values for all
pairwise comparisons, as indicated by the symbols, were done by Bonferroni-Holm–corrected …

Myocardial triglyceride content and epicardial fat mass in human obesity: relationship to left ventricular function and serum free fatty acid levels

…, J Knuuti, P Nuutila, R Parkkola, P Iozzo - The Journal of …, 2006 - academic.oup.com
Context and Objective: Ectopic fat accumulation within and around the myocardial wall has
been implicated in the pathogenesis of heart disease in obesity. We evaluated myocardial …

Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans

…, R Huupponen, P Nuutila - The Journal of …, 2002 - academic.oup.com
… were lower in obese than in nonobese subjects (P < 0.01). Compared with nonobese, the
obese … higher in visceral fat depots than in sc regions (P < 0.01). Both sc and visceral adipose …

Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss, comorbidities, and reflux at 10 years in adult patients with obesity: the …

…, P Peromaa-Haavisto, M Leivonen, P Nuutila… - JAMA …, 2022 - jamanetwork.com
… after LRYGB (8% vs 24%;P = .04). Esophagitis was more prevalent after LSG (31% vs 7%;P
< .001) with no statistically significant difference in BE (4% vs 4%;P = .29). The overall …

Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo.

P Nuutila, VA Koivisto, J Knuuti… - The Journal of …, 1992 - Am Soc Clin Investig
Positron emission tomography permits noninvasive measurement of regional glucose uptake
in vivo in humans. We employed this technique to determine the effect of FFA on glucose …