User profiles for P. O'Donnell

Patricio O'Donnell

University of Maryland School of Medicine
Verified email at umaryland.edu
Cited by 14733

Preparation of microspheres by the solvent evaporation technique

PB O'Donnell, JW McGinity - Advanced drug delivery reviews, 1997 - Elsevier
O'Donnell and coworkers [36]prepared multiphase microspheres of poly(dl-lactic-co-glycolic
acid) by a multiple emulsion potentiometric dispersion technique. Water soluble …

Implementing genomic medicine in the clinic: the future is here

…, C Marsh, D Mrazek, MF Murray, PH O'Donnell… - Genetics in …, 2013 - nature.com
Although the potential for genomics to contribute to clinical care has long been anticipated,
the pace of defining the risks and benefits of incorporating genomic findings into medical …

Post-transplantation cyclophosphamide for tolerance induction in HLA-haploidentical bone marrow transplantation

L Luznik, PV O'Donnell, EJ Fuchs - Seminars in oncology, 2012 - Elsevier
Allogeneic hematopoietic stem cell transplantation (alloSCT) is a potentially curative
therapy for many hematologic and immunologic diseases. Further, partial or full donor …

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a …

…, AV Balar, A Necchi, N Dawson, PH O'Donnell… - The Lancet, 2016 - thelancet.com
Background Patients with metastatic urothelial carcinoma have few treatment options after
failure of platinum-based chemotherapy. In this trial, we assessed treatment with atezolizumab…

[PDF][PDF] Comprehensive molecular characterization of muscle-invasive bladder cancer

…, AJ Mungall, JB Myers, R Naresh, PH O'Donnell… - Cell, 2017 - cell.com
We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …

Effect of weekly subcutaneous semaglutide vs daily liraglutide on body weight in adults with overweight or obesity without diabetes: the STEP 8 randomized clinical …

…, E Klein, K Laufer, P O'Donnell, P Rosenblit, P Toth… - Jama, 2022 - jamanetwork.com
… Two-sided 95% CIs and corresponding P values were calculated for all statistical analysis
results. Statistical analyses were performed using SAS version 9.4 (SAS Institute Inc). Efficacy …

[HTML][HTML] HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation …

L Luznik, PV O'Donnell, HJ Symons, AR Chen… - Biology of Blood and …, 2008 - Elsevier
We evaluated the safety and efficacy of high-dose, posttransplantation cyclophosphamide (Cy)
to prevent graft rejection and graft-versus-host disease (GVHD) after outpatient …

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

…, F Berisha, R Pollock, P O'Donnell… - The Journal of …, 2011 - Wiley Online Library
Somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 occur in gliomas and acute
myeloid leukaemia (AML). Since patients with multiple enchondromas have occasionally …

First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single …

AV Balar, D Castellano, PH O'Donnell, P Grivas… - The Lancet …, 2017 - thelancet.com
… Peter H O'Donnell, MD Peter H O'Donnell … overall survival compared with chemotherapy
(10 months vs 7 months; p=0·0022) in patients with recurrent, advanced urothelial cancer. …

Ethylene as a signal mediating the wound response of tomato plants

PJ O'donnell, C Calvert, R Atzorn, C Wasternack… - Science, 1996 - science.org
Plants respond to physical injury, such as that caused by foraging insects, by synthesizing
proteins that function in general defense and tissue repair. In tomato plants, one class of …