… <0.001), and further reducing sodium intake from 2.4 to 1.5 g/d yielded additional reductions
of 4.6 mm Hg (P<0.001). The DASH diet was associated with a significantly lower SBP at …

High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN-HFS) is the
preferred surgical treatment for advanced Parkinson's disease. In the 15 years since its …

… Krack P, Pollak P. Limousin … Krack P, Limousin P. Benabid AL. Pollak P. Chronic stimulation
of subthalamic nucleus improvcs levodopa~induced dyskinesias in Parkinson‘s disease. …

… for motor function while off medication improved by 54 percent (P<0.001) and those for
activities of daily living improved by 49 percent (P<0.001). Speech was the only motor function for …

Background In many patients with idiopathic Parkinson's disease, treatment with levodopa
is complicated by fluctuations between an “off” period (also referred to as “off medication”), …

Background Mutations in the parkin gene have recently been identified in patients with early-onset
Parkinson's disease, but the frequency of the mutations and the associated …

Deep brain stimulation (DBS) is associated with significant improvement of motor complications
in patients with severe Parkinson's disease after some 6–12 months of treatment. Long-…

The α-synuclein gene (SNCA) has been implicated in autosomal dominant forms of Parkinson's
disease. We screened 119 individuals from families with this rare form of the disease for …

In monkeys rendered parkinsonian, lesions and electrical stimulation of the subthalamic
nucleus reduce all major motor disturbances. The effect of electrical stimulation of the …

The usefulness of high-frequency stimulation of the ventral intermediate nucleus (Vim) as
the first neurosurgical procedure in disabling tremor was assessed in 26 patients with …