Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis
…, A Rovira, JF Sumowski, P Valsasina… - The Lancet …, 2015 - thelancet.com
In patients with multiple sclerosis (MS), grey matter damage is widespread and might underlie
many of the clinical symptoms, especially cognitive impairment. This relation between …
many of the clinical symptoms, especially cognitive impairment. This relation between …
MRI monitoring of pathological changes in the spinal cord in patients with multiple sclerosis
…, P Valsasina, JCW Brooks, A Bischof, P Eisele… - The Lancet …, 2015 - thelancet.com
The spinal cord is a clinically important site that is affected by pathological changes in most
patients with multiple sclerosis; however, imaging of the spinal cord with conventional MRI …
patients with multiple sclerosis; however, imaging of the spinal cord with conventional MRI …
Default-mode network dysfunction and cognitive impairment in progressive MS
… (p = 0.01) and PcG (p = 0.02), while patients with PPMS had reduced activity in the PcG (p =
0.008) and the ACC (p = … with SPMS had increased ACC activity (p = 0.04). Reduction of RS …
0.008) and the ACC (p = … with SPMS had increased ACC activity (p = 0.04). Reduction of RS …
[HTML][HTML] Task-and resting-state fMRI studies in multiple sclerosis: from regions to systems and time-varying analysis. Current status and future perspective
MA Rocca, MM Schoonheim, P Valsasina… - Neuroimage: Clinical, 2022 - Elsevier
Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …
features extensive functional brain changes that are poorly understood but relate strongly to …
Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks
…, H Rasoanandrianina, JC Brisset, P Valsasina… - Neuroimage, 2019 - Elsevier
… When averaging the performance metrics across all contrasts, the centerline detection
using CNN 1 significantly outperformed the SVM-based method (p < 0.001), as shown by the …
using CNN 1 significantly outperformed the SVM-based method (p < 0.001), as shown by the …
Large-scale neuronal network dysfunction in relapsing-remitting multiple sclerosis
… the SN vs the ECN (p = 0.03), and the right WMN vs the primary visual RSN (p = 0.02). They
… vs the DMN (p = 0.03), and the left WMN vs the sensorimotor network I (p < 0.001) (figure 2). …
… vs the DMN (p = 0.03), and the left WMN vs the sensorimotor network I (p < 0.001) (figure 2). …
Multiple sclerosis: effects of cognitive rehabilitation on structural and functional MR imaging measures—an explorative study
…, R Capra, C Stampatori, E Pagani, P Valsasina… - Radiology, 2012 - pubs.rsna.org
… At follow-up, a tendency toward a significant increase in accuracy (P = .06) and a shortening
of the reaction time (P = .05) during the Stroop incongruent condition was detected in the …
of the reaction time (P = .05) during the Stroop incongruent condition was detected in the …
The organization of intrinsic brain activity differs between genders: A resting‐state fMRI study in a large cohort of young healthy subjects
… For all the analyses run with SPM, results were assessed at a threshold of P < 0.05 corrected
for multiple comparisons (family-wise error [FWE]). Results were also tested at P < 0.001 (…
for multiple comparisons (family-wise error [FWE]). Results were also tested at P < 0.001 (…
Brain network connectivity assessed using graph theory in frontotemporal dementia
F Agosta, S Sala, P Valsasina, A Meani, E Canu… - Neurology, 2013 - AAN Enterprises
… While the traditional FDR approach involves sequential p value rejection based on observed
data, 27 which fixes the error rate and estimates the corresponding region of rejection, the …
data, 27 which fixes the error rate and estimates the corresponding region of rejection, the …
A multicenter assessment of cervical cord atrophy among MS clinical phenotypes
…, MA Horsfield, S Sala, M Copetti, P Valsasina… - Neurology, 2011 - AAN Enterprises
Objective: In this multicenter study, a new semiautomatic method for segmenting the cervical
cord from C2 to C5 was used to investigate the correlation between cord atrophy and …
cord from C2 to C5 was used to investigate the correlation between cord atrophy and …