User profiles for P.M. Thompson

Paul Thompson

Professor of Neurology & Psychiatry, Imaging Genetics Center, USC
Verified email at usc.edu
Cited by 193346

The clinical use of structural MRI in Alzheimer disease

…, CR Jack Jr, P Scheltens, PM Thompson - Nature Reviews …, 2010 - nature.com
Structural imaging based on magnetic resonance is an integral part of the clinical assessment
of patients with suspected Alzheimer dementia. Prospective data on the natural history of …

Mapping brain asymmetry

AW Toga, PM Thompson - Nature Reviews Neuroscience, 2003 - nature.com
Brain asymmetry has been observed in animals and humans in terms of structure, function
and behaviour. This lateralization is thought to reflect evolutionary, hereditary, developmental, …

Mapping brain maturation

AW Toga, PM Thompson, ER Sowell - Trends in neurosciences, 2006 - cell.com
Human brain maturation is a complex, lifelong process that can now be examined in detail
using neuroimaging techniques. Ongoing projects scan subjects longitudinally with structural …

Dynamic mapping of human cortical development during childhood through early adulthood

…, JL Rapoport, PM Thompson - Proceedings of the …, 2004 - National Acad Sciences
We report the dynamic anatomical sequence of human cortical gray matter development
between the age of 4–21 years using quantitative four-dimensional maps and time-lapse …

Mapping cortical change across the human life span

ER Sowell, BS Peterson, PM Thompson… - Nature …, 2003 - nature.com
We used magnetic resonance imaging and cortical matching algorithms to map gray matter
density (GMD) in 176 normal individuals ranging in age from 7 to 87 years. We found a …

Growth patterns in the developing brain detected by using continuum mechanical tensor maps

PM Thompson, JN Giedd, RP Woods, D MacDonald… - Nature, 2000 - nature.com
The dynamic nature of growth and degenerative disease processes requires the design of
sensitive strategies to detect, track and quantify structural change in the brain in its full spatial …

In vivo evidence for post-adolescent brain maturation in frontal and striatal regions

ER Sowell, PM Thompson, CJ Holmes… - Nature …, 1999 - nature.com
We spatially and temporally mapped brain maturation between adolescence and young
adulthood using a whole-brain, voxel-by-voxel statistical analysis of high-resolution structural …

Longitudinal mapping of cortical thickness and brain growth in normal children

ER Sowell, PM Thompson, CM Leonard… - Journal of …, 2004 - Soc Neuroscience
Recent advances in magnetic resonance imaging (MRI) technology now allow the tracing of
developmental changes in the brains of children. We applied computer-matching algorithms …

Sexual dimorphism of brain developmental trajectories during childhood and adolescence

…, J Lerch, AP Zijdenbos, AC Evans, PM Thompson… - Neuroimage, 2007 - Elsevier
Human total brain size is consistently reported to be ∼8–10% larger in males, although
consensus on regionally specific differences is weak. Here, in the largest longitudinal pediatric …

Genetic influences on brain structure

PM Thompson, TD Cannon, KL Narr, T Van Erp… - Nature …, 2001 - nature.com
Here we report on detailed three-dimensional maps revealing how brain structure is
influenced by individual genetic differences. A genetic continuum was detected in which brain …