Status epilepticus (SE) treatment strategies vary substantially from one institution to another
due to the lack of data to support one treatment over another. To provide guidance for the …

Microdialysis (MD) was introduced as an intracerebral sampling method for clinical neurosurgery
by Hillered et al. and Meyerson et al. in 1990. Since then MD has been embraced as a …

This article reviews the pathophysiology of mild traumatic brain injury, and the findings from
EEG and quantitative EEG (QEEG) testing after such an injury. Research on the clinical …

Background Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF)
has the potential to identify a broad range of pathogens in a single test. Methods In a 1-year, …

Object. The early pathophysiological features of traumatic brain injury observed in the intensive
care unit (ICU) have been described in terms of altered cerebral blood flow, altered brain …

✓ Experimental traumatic brain injury studies have shown that cerebral hyperglycolysis is a
pathophysiological response to injury-induced ionic and neurochemical cascades. This …

Objective: To determine whether early seizures that occur frequently after intracerebral
hemorrhage (ICH) lead to increased brain edema as manifested by increased midline shift. …

… seizures by the neuro-ICU nurse or neurointensivist, during the EEG screening by the
neurointensivist, or by total power trend seizure detection method (previously described by Vespa …

Background and Purpose— Information regarding the histological structure of thromboemboli
that cause acute stroke provides insight into pathogenesis and clinical management. …

The neurologic morbidity of delayed ischemic deficits from vasospasm following aneurysmal
subarachnoid hemorrhage (SAH) continues to be the most debilitating complication from …