User profiles for P.S. LaViolette

Peter S LaViolette

Professor of Radiology, Biophysics, and Biomedical Engineering, Medical College of …
Verified email at mcw.edu
Cited by 9232

Functional alterations in memory networks in early Alzheimer's disease

…, M Pihlajamaki, P Vannini, PS LaViolette… - Neuromolecular …, 2010 - Springer
The hallmark clinical symptom of early Alzheimer’s disease (AD) is episodic memory impairment.
Recent functional imaging studies suggest that memory function is subserved by a set …

[HTML][HTML] Photodynamic therapy (PDT) for malignant brain tumors–where do we stand?

…, SM Lew, AW Girotti, S Jogal, PS LaViolette… - Photodiagnosis and …, 2015 - Elsevier
… a photosensitizer from its ground state (PS) to a singlet excited state ( 1 PS), followed by
intersystem crossing (ISC) to a long-lived triplet excited state ( 3 PS). The latter can then interact …

[PDF][PDF] Amyloid deposition is associated with impaired default network function in older persons without dementia

RA Sperling, PS LaViolette, K O'Keefe, J O'Brien… - Neuron, 2009 - cell.com
Alzheimer's disease (AD) has been associated with functional alterations in a distributed
network of brain regions linked to memory function, with a recent focus on the cortical regions …

[PDF][PDF] Glioma progression is shaped by genetic evolution and microenvironment interactions

…, MCM Kouwenhoven, A Lasorella, PS LaViolette… - Cell, 2022 - cell.com
The factors driving therapy resistance in diffuse glioma remain poorly understood. To
identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …

Longitudinal molecular trajectories of diffuse glioma in adults

…, H Kim, MCM Kouwenhoven, PS LaViolette… - Nature, 2019 - nature.com
The evolutionary processes that drive universal therapeutic resistance in adult patients with
diffuse glioma remain unclear 1 , 2 . Here we analysed temporally separated DNA-…

Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline

JL O'brien, KM O'keefe, PS LaViolette, AN DeLuca… - Neurology, 2010 - AAN Enterprises
Background: Previous cross-sectional fMRI studies in subjects with prodromal Alzheimer
disease (AD) have reported variable results, ranging from hypoactivation, similar to patients …

Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity

…, JM Connelly, C Quinsey, PS LaViolette… - Journal of Magnetic …, 2010 - Wiley Online Library
Purpose: To present comprehensive examinations of the assumptions made in functional
diffusion map (fDM) analyses and provide a biological basis for fDM classification. Materials …

An integrated iterative annotation technique for easing neural network training in medical image analysis

…, D Govind, SD McGarry, PS LaViolette… - Nature machine …, 2019 - nature.com
LaVioletteLaViolettePS is responsible for the overall coordination of the project,
mentoring and formalizing the image analysis concept and oversaw manuscript preparation. …

Vascular interventional radiology-guided photothermal therapy of colorectal cancer liver metastasis with theranostic gold nanorods

…, G Sharma, JM Jagtap, VR Gogineni, PS LaViolette… - ACS …, 2018 - ACS Publications
We report sub-100 nm optical/magnetic resonance (MR)/X-ray contrast-bearing theranostic
nanoparticles (TNPs) for interventional image-guided photothermal therapy (PTT) of solid …

Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high …

PS LaViolette, NJ Mickevicius, EJ Cochran… - Neuro …, 2014 - academic.oup.com
Background Recent conflicting reports have found both brain tumor hypercellularity and
necrosis in regions of restricted diffusion on MRI-derived apparent diffusion coefficient (ADC) …