User profiles for Paul D. Griffiths

Paul D Griffiths

University of Sheffield
Verified email at sheffield.ac.uk
Cited by 14983

[HTML][HTML] Valganciclovir for symptomatic congenital cytomegalovirus disease

…, PH Dennehy, A Finn, PD Griffiths… - … England Journal of …, 2015 - Mass Medical Soc
Background The treatment of symptomatic congenital cytomegalovirus (CMV) disease with
intravenous ganciclovir for 6 weeks has been shown to improve audiologic outcomes at 6 …

Genetic content of wild-type human cytomegalovirus

…, D Gatherer, VC Emery, PD Griffiths… - Journal of General …, 2004 - microbiologyresearch.org
The genetic content of wild-type human cytomegalovirus was investigated by sequencing
the 235 645 bp genome of a low passage strain (Merlin). Substantial regions of the genome (…

Definitions of cytomegalovirus infection and disease in transplant patients for use in clinical trials

…, RR Razonable, V Miller, PD Griffiths… - Clinical Infectious …, 2016 - academic.oup.com
Cytomegalovirus (CMV) infection and disease are important causes of morbidity and
mortality in transplant recipients. For the purpose of developing consistent reporting of CMV …

Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation

…, AV Cope, D Gor, AF Hassan-Walker, PD Griffiths - The Lancet, 2000 - thelancet.com
Background Cytomegalovirus (CMV) continues to be a major problem post-transplantation;
early markers for predicting patients at risk of CMV disease are needed. Peak CMV load in …

Investigating the functional anatomy of empathy and forgiveness

…, SA Spence, JFW Deakin, N Tarrier, PD Griffiths… - …, 2001 - journals.lww.com
Previous functional brain imaging studies suggest that the ability to infer the intentions and
mental states of others (social cognition) is mediated by medial prefrontal cortex. Little is …

[HTML][HTML] Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial

PD Griffiths, A Stanton, E McCarrell, C Smith, M Osman… - The Lancet, 2011 - thelancet.com
Background Cytomegalovirus end-organ disease can be prevented by giving ganciclovir
when viraemia is detected in allograft recipients. Values of viral load correlate with …

Advances in the understanding of the pathogenesis and epidemiology of herpes zoster

…, J Breuer, MJ Levin, AL Oaklander, PD Griffiths - Journal of clinical …, 2010 - Elsevier
The primary varicella zoster virus (VZV) infection results in chickenpox (varicella), which is
transmitted via the airborne route. VZV is highly infectious, but in the USA the incidence of …

Cytomegalovirus

PD Griffiths - Principles and practice of clinical virology, 1999 - Wiley Online Library
Cytomegalovirus (CMV) infections were first described in the early years of the twentieth
century when the typical owl's eye intranuclear inclusions were found by histopathologists in …

Neuro‐epileptic determinants of autism spectrum disorders in tuberous sclerosis complex

PF Bolton, RJ Park, JNP Higgins, PD Griffiths, A Pickles - Brain, 2002 - academic.oup.com
Tuberous sclerosis is one of the few established medical causes of autism spectrum
disorder and is a unique neurogenetic model for testing theories about the brain basis of the …

Association of tuberous sclerosis of temporal lobes with autism and atypical autism

PF Bolton, PD Griffiths - The Lancet, 1997 - thelancet.com
Background Tuberous sclerosis (TS) is a multisystem genetic disorder that is associated
with mental retardation, autism, and atypical autism. We investigated the basis for these …