Nerve crush is a commonly used experimental model in the rat; however, a standard method
of inducing this injury has not been defined. This study examined six crush techniques that …

Background: A novel autosomal recessive condition, dilated cardiomyopathy with ataxia (DCMA)
syndrome, has been identified in the Canadian Dariusleut Hutterite population, …

Purpose: RG7112 is a small-molecule MDM2 antagonist. MDM2 is a negative regulator of the
tumor suppressor p53 and frequently overexpressed in leukemias. Thus, a phase I study of …

Although the pathogenic mechanisms involved in predisposing individuals to hypertension
are not well defined, evidence is accumulating that suggests a strong genetic transmission. …

This article is an exploration of the National Institute on Drug Abuse (NIDA) Technical Review
on the role of glutamatergic systems in the development of opiate addiction. The effects of “…

The study evaluated the relationship between age and frontal and temporal lobe volumes in
young cohorts of cocaine-dependent (CD), amphetamine-dependent (Am), and normal …

We conducted a multi-site, placebo-controlled, randomized double-blind clinical trial
comparing bupropion HCL (300 mg/day) to placebo for the treatment of cocaine dependence in …

Background and objective: In clinical settings with fixed resources allocated to predictive
genetic testing for high-risk cancer predisposition genes, optimal strategies for mutation …

In recent years, simulation has increasingly underpinned the acquisition of pre-clinical skills
by undergraduate medical imaging (diagnostic radiography) students. This project aimed to …

Background: Animal and human newborn studies suggest that exposure to cocaine in utero
delays glial maturation and white matter myelination. Postmortem data show that in the …