Immune checkpoint inhibitor (ICI) treatments benefit some patients with metastatic cancers,
but predictive biomarkers are needed. Findings in selected cancer types suggest that tumor …

Brain malignancies encompass a range of primary and metastatic cancers, including low-grade
and high-grade gliomas and brain metastases (BrMs) originating from diverse …

PURPOSE: NovoTTF-100A is a portable device delivering low-intensity, intermediate
frequency electric fields via non-invasive, transducer arrays. Tumour Treatment Fields (TTF), a …

Purpose: To determine if adjnvant interstitial hyperthennia (HT) significantly improves survival
of patients with moma undergoing hrachytherapy boost after conventional radiotherapy. …

We report genomic analysis of 300 meningiomas, the most common primary brain tumors,
leading to the discovery of mutations in TRAF7, a proapoptotic E3 ubiquitin ligase, in nearly …

Purpose: Because whole brain radiotherapy (WBRT) may cause dementia in long-term
survivors, selected patients with brain metastases may benefit from initial treatment with …

Extensive transcriptional and ontogenetic diversity exists among normal tissue-resident
macrophages, with unique transcriptional profiles endowing the cells with tissue-specific …

Poliovirus neuropathogenicity depends on sequences within the 5′ nontranslated region
of the virus. Exchange of the poliovirus internal ribosomal entry site with its counterpart from …

Purpose : To review the experience at University of California Lawrence Berkeley Laboratory
in using charged particles to irradiate primary neoplasms of the skull base and those …

OBJECTIVE: To determine the selection factors for and results of second resections performed
to treat recurrent glioblastoma multiforme (GM), we studied 301 patients with GM who …