Reversible middle cerebral artery occlusion without craniectomy in rats.
EZ Longa, PR Weinstein, S Carlson, R Cummins - stroke, 1989 - Am Heart Assoc
To develop a simple, relatively noninvasive small-animal model of reversible regional
cerebral ischemia, we tested various methods of inducing infarction in the territory of the right …
cerebral ischemia, we tested various methods of inducing infarction in the territory of the right …
Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia
…, SJ Won, M Neumann, D Hu, L Zhou, PR Weinstein… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— Evidence suggests that activated microglia are detrimental to the
survival of new hippocampal neurons, whereas blocking inflammation has been shown to …
survival of new hippocampal neurons, whereas blocking inflammation has been shown to …
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction
…, R Mestril, W Dillmann, PR Weinstein… - Annals of Neurology …, 2000 - Wiley Online Library
Increased expression of heat shock protein 70 (HSP70) in the brain has been extensively
documented in association with a variety of insults, including ischemia, and is suggested to …
documented in association with a variety of insults, including ischemia, and is suggested to …
Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury
…, ZS Vexler, DM Ferriero, PR Weinstein… - Journal of cerebral …, 2005 - journals.sagepub.com
Apoptosis is implicated in neonatal hypoxic/ischemic (H/I) brain injury among various forms
of cell death. Here we investigate whether overexpression of heat shock protein (Hsp) 70, an …
of cell death. Here we investigate whether overexpression of heat shock protein (Hsp) 70, an …
Diffusion-Weighted Magnetic Resonance Imaging of Acute Focal Cerebral Ischemia: Comparison of Signal Intensity with Changes in Brain Water and Na+,K+ …
…, PH Chan, PR Weinstein - Journal of Cerebral …, 1994 - journals.sagepub.com
Diffusion-weighted magnetic resonance (MR) images from rats during acute cerebral
ischemia induced by middle cerebral artery occlusion were analyzed for correspondence with …
ischemia induced by middle cerebral artery occlusion were analyzed for correspondence with …
The “presyrinx” state: a reversible myelopathic condition that may precede syringomyelia
…, WP Dillon, C Cobbs, PR Weinstein - American journal of …, 1999 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Alteration of CSF flow has been proposed to be an
important mechanism leading to the development of syringomyelia. We hypothesize that a “…
important mechanism leading to the development of syringomyelia. We hypothesize that a “…
Irradiation attenuates neurogenesis and exacerbates ischemia‐induced deficits
…, Y Matsumori, Z Liu, PR Weinstein… - Annals of Neurology …, 2004 - Wiley Online Library
Increased neurogenesis after cerebral ischemia suggests that functional recovery after stroke
may be attributed, in part, to neural regeneration. In this study, we investigated the role of …
may be attributed, in part, to neural regeneration. In this study, we investigated the role of …
Mild intraischemic hypothermia reduces postischemic hyperperfusion, delayed postischemic hypoperfusion, blood-brain barrier disruption, brain edema, and neuronal …
…, SH Graham, PR Weinstein - Journal of Cerebral …, 1994 - journals.sagepub.com
Mild to moderate hypothermia (30–33C) reduces brain injury after brief (<2-h) periods of
focal ischemia, but its effectiveness in prolonged temporary ischemia is not fully understood. …
focal ischemia, but its effectiveness in prolonged temporary ischemia is not fully understood. …
Changes in transcranial motor evoked potentials during intramedullary spinal cord tumor resection correlate with postoperative motor function
…, N Gupta, AT Parsa, MW McDermott, PR Weinstein - …, 2005 - journals.lww.com
OBJECTIVE: Intraoperative monitoring of transcranial motor evoked potentials (TcMEPs)
has been investigated recently as a means of preventing motor deficits associated with …
has been investigated recently as a means of preventing motor deficits associated with …
Microsurgical treatment of symptomatic sacral Tarlov cysts
…, BM McCormack, JM Corroo, PR Weinstein - …, 2000 - journals.lww.com
OBJECTIVE: Providing relief of symptomatic radiculopathy resulting from sacral perineural
cysts has proven difficult. Our goal was to improve the treatment of these cysts with …
cysts has proven difficult. Our goal was to improve the treatment of these cysts with …