[HTML][HTML] Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive …

L Schmaal, DP Hibar, PG Sämann, GB Hall… - Molecular …, 2017 - nature.com
The neuro-anatomical substrates of major depressive disorder (MDD) are still not well
understood, despite many neuroimaging studies over the past few decades. Here we present the …

Common genetic variants influence human subcortical brain structures

…, R Roiz-Santiañez, EJ Rose, A Salami, PG Sämann… - Nature, 2015 - nature.com
The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

[HTML][HTML] ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

…, PG Sämann, L Schmaal, G Schumann… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging
Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across …

Development of the brain's default mode network from wakefulness to slow wave sleep

PG Sämann, R Wehrle, D Hoehn… - Cerebral …, 2011 - academic.oup.com
Falling asleep is paralleled by a loss of conscious awareness and reduced capacity to
process external stimuli. Little is known on sleep-associated changes of spontaneously …

[HTML][HTML] Novel genetic loci associated with hippocampal volume

…, EJ Rose, NA Royle, T Rundek, PG Sämann… - Nature …, 2017 - nature.com
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …

Neural correlates of dream lucidity obtained from contrasting lucid versus non-lucid REM sleep: a combined EEG/fMRI case study

…, SP Koch, F Holsboer, A Steiger, H Obrig, PG Sämann… - Sleep, 2012 - academic.oup.com
Philipp G. Sämann, MD … Sämann, Michael Czisch, Neural Correlates of Dream Lucidity
Obtained from Contrasting Lucid versus Non-Lucid REM Sleep: A Combined EEG/fMRI Case …

Development of a large-scale functional brain network during human non-rapid eye movement sleep

…, M Dresler, R Wehrle, PG Sämann… - Journal of …, 2010 - Soc Neuroscience
Graph theoretical analysis of functional magnetic resonance imaging (fMRI) time series has
revealed a small-world organization of slow-frequency blood oxygen level-dependent (BOLD…

[HTML][HTML] White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group

…, J Repple, A Roos, MD Sacchet, PG Sämann… - Molecular …, 2020 - nature.com
Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent, …

Novel genetic loci underlying human intracranial volume identified through genome-wide association

…, EJ Rose, NA Royle, T Rundek, PG Sämann… - Nature …, 2016 - nature.com
Intracranial volume reflects the maximally attained brain size during development, and remains
stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain …

Genetic architecture of subcortical brain structures in 38,851 individuals

…, GI De Zubicaray, TY Wong, L Shen, PG Sämann… - Nature …, 2019 - nature.com
Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens, …