User profiles for Q.-D. Wang

Qing-Dong Wang

Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM) …
Verified email at astrazeneca.com
Cited by 4237

Pharmacological possibilities for protection against myocardial reperfusion injury

QD Wang, J Pernow, PO Sjöquist… - Cardiovascular …, 2002 - academic.oup.com
Reperfusion through thrombolysis or percutananeous coronary angioplasty is standard
treatment in impending acute myocardial infarction. Although restoration of blood flow to the …

HST/NICMOS Paschen-α Survey of the Galactic Centre: Overview

QD Wang, H Dong, A Cotera, S Stolovy… - Monthly Notices of …, 2010 - academic.oup.com
We have recently carried out the first wide-field hydrogen Paschen-α line imaging survey of
the Galactic Centre using the Near Infrared Camera and Multi-Object Spectrometer (NICMOS…

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

…, EJ Needham, QD Wang… - Proceedings of the …, 2017 - National Acad Sciences
The mammalian heart undergoes maturation during postnatal life to meet the increased
functional requirements of an adult. However, the key drivers of this process remain poorly …

Endothelin in myocardial ischaemia and reperfusion

J Pernow, QD Wang - Cardiovascular research, 1997 - academic.oup.com
Endothelin-1 (ET-1) is an extremely potent vasoconstrictor peptide derived from vascular
endothelial cells. ET-1 can also be produced by other cell types such as smooth muscle cells …

Dissecting X-ray–emitting gas around the center of our galaxy

QD Wang, MA Nowak, SB Markoff, FK Baganoff… - Science, 2013 - science.org
Most supermassive black holes (SMBHs) are accreting at very low levels and are difficult to
distinguish from the galaxy centers where they reside. Our own Galaxy’s SMBH provides an …

Tension-compression asymmetry and the underlying slip/twinning activity in extruded Mg–Y sheets

…, GH Huang, H Zhou, J Zheng, QD Wang - International Journal of …, 2021 - Elsevier
The asymmetric mechanical response and corresponding statistical grain-scale slip/twinning
activity for extruded Mg-(0~5 wt%)Y sheets during room-temperature uniaxial tension and …

Ultrastrong Mg alloy via nano-spaced stacking faults

…, WZ Xu, H Yuan, MH Tsai, QD Wang… - Materials Research …, 2013 - Taylor & Francis
Mg alloys are among the lightest alloys but they are usually weak. Here we report a new
mechanism to make them ultrastrong while maintaining good ductility. Stacking faults with …

Discovery of an ultrafast X-ray pulsar in the supernova remnant N157B

…, W Zhang, J Middleditch, QD Wang - The Astrophysical …, 1998 - iopscience.iop.org
We present the serendipitous discovery of 16 ms pulsed X-ray emission from the Crab-like
supernova remnant N157B in the Large Magellanic Cloud. This is the fastest spinning pulsar …

Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair

…, X Han, Y Li, K Liu, M Shi, L Lai, R Sun, QD Wang… - Science, 2021 - science.org
INTRODUCTION Cell proliferation is a fundamental process in all multicellular organisms
that is required to enable development, tissue homeostasis, tissue repair, and tissue …

Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis

M Han, Z Liu, L Liu, X Huang, H Wang, W Pu, E Wang… - Nature Genetics, 2023 - nature.com
After severe heart injury, fibroblasts are activated and proliferate excessively to form scarring,
leading to decreased cardiac function and eventually heart failure. It is unknown, however, …