Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month …

…, G Owen, A Durr, BR Leavitt, RA Roos… - The Lancet …, 2013 - thelancet.com
Background TRACK-HD is a multinational prospective observational study of Huntington's
disease (HD) that examines clinical and biological findings of disease progression in …

Prevalence of subjective dysphagia in community residents aged over 87.

…, W Van Beek, J Haan, RA Roos… - BMJ: British Medical …, 1990 - ncbi.nlm.nih.gov
Dysphagia may have many implications for social and physical health; dysphagic people
often have malnutrition and airway infections due to aspiration, and their reluctance to eat …

Recommendations for the predictive genetic test in Huntington's disease

…, A Jones, A Martinez‐Descales, RA Roos… - Clinical …, 2013 - Wiley Online Library
The 1994 predictive test guidelines for Huntington’s disease (HD) were published by an ad
hoc Committee comprising representatives from the World Federation of Neurology (WFN) …

Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease

…, EP Hart, A Dürr, BR Leavitt, RA Roos… - Journal of Neurology …, 2012 - jnnp.bmj.com
Background Deterioration of cognitive functioning is a debilitating symptom in many
neurodegenerative diseases, such as Huntington's disease (HD). To date, there are no effective …

Diurnal effects of motor activity and fatigue in Parkinson's disease.

…, HA Middelkoop, GA Kerkhof, RA Roos - Journal of neurology …, 1993 - jnnp.bmj.com
Wrist motor activity was monitored continuously in 65 patients with Parkinson's disease (PD)
to assess the influence of disease severity and excessive fatigue on the diurnal motor …

Clinical and genetic analysis of a large Dutch family with autosomal dominant vascular retinopathy, migraine and Raynaud's phenomenon.

…, CW Storimans, JB Lanser, RA Roos… - Brain: a journal of …, 1998 - academic.oup.com
We describe an extended Dutch family with a new hereditary disorder: autosomal dominant
vascular retinopathy, migraine and Raynaud's phenomenon. Information was obtained on …

[PDF][PDF] A review of cognition in Huntington's disease

…, HA Middelkoop, RA Roos - Front Biosci …, 2013 - scholarlypublications …
With the prospect of potential treatments for Huntington’s disease (HD), non-invasive markers
of disease progression are needed. Cognitive impairment has long been recognised as …

Autonomic nervous system dysfunction in Parkinson's disease: relationships with age, medication, duration, and severity.

…, B Kremer, BJ Van Hilten, RA Roos - Journal of Neurology …, 1993 - jnnp.bmj.com
Heart rate variability at rest, during deep breathing, or standing up and with the Valsalva
manoeuvre did not differ significantly between 67 patients with idiopathic Parkinson's disease (…

Duration of illness in Huntington's disease is not related to age at onset.

RA Roos, J Hermans, M Vegter-Van Der Vlis… - Journal of Neurology …, 1993 - jnnp.bmj.com
The age at onset and duration of illness were studied in patients with Huntington's disease
in the Leiden Roster which at 1 July 1990 contained 2787 patients. Of 1106 patients, 800 …

The interpretation of dysprosody in patients with Parkinson's disease.

…, ME Van der Linden, OJ Buruma, RA Roos - Journal of Neurology …, 1991 - jnnp.bmj.com
Prosodic features in the speech production of 21 patients with idiopathic Parkinson's disease
were tested. The appreciation of vocal and facial expression was also examined in the …