… , and we would expect this to increase R and decrease the net MR signal. Numerical
simulations suggest that a reasonable approximation is to assume that R is proportional to V, the …

A general mathematical model for the delivery of O 2 to the brain is presented, based on the
assumptions that all of the brain capillaries are perfused at rest and that all of the oxygen …

The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

A biomechanical model is presented for the dynamic changes in deoxyhemoglobin content
during brain activation. The model incorporates the conflicting effects of dynamic changes in …

Recently, several implementations of arterial spin labeling (ASL) techniques have been
developed for producing MRI images sensitive to local tissue perfusion. For quantitation of …

… In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard
Buxton–a leading authority on fMRI–provides an invaluable guide to how fMRI works, from …

We investigated the cortical mechanisms of visual-spatial attention while subjects discriminated
patterned targets within distractor arrays. Functional magnetic resonance imaging (fMRI) …

In the pulsed arterial spin labeling (ASL) techniques EPISTAR, PICORE, and FAIR,
subtraction of two images in which inflowing blood is first tagged and then not tagged yields a …

… subject (mean r = 0.56; mean percent signal change = 1.58)—was not active during the
Motor task [mean r = 0.15; mean percent signal change = 0.38; matched-pairs t 5 (comparing …

Using a one‐dimensional rapid imaging technique, we have found that injection of lanthanide
chelates such as Gd(DTPA) 2− leads to a significant decrease (50%) in rat brain signal …