trkB is a tyrosine protein kinase gene highly related to trk, a proto-oncogene that encodes a
receptor for nerve growth factor (NGF) and neurotrophin-3(NT-3). t&B expression is confined …

We previously identified two tyrosine protein kinase genes, designated frk and f&B, that code
for putative neurogenic cell surface receptors. In this study, we report that the mouse frkB …

Two classes of receptors with distinct affinities for nerve growth factor (NGF) have been
identified. The low affinity receptor (Kd-= 10. 9 to 10-aM) is a cysteinerich glycoprotein encoded …

We report the isolation and molecular characterization of t&C, a new member of the trk
family of tyrosine protein kinase genes. t&C is preferentially expressed in the brain. In situ …

The glucocorticoid receptor (Gr, encoded by the gene Grl1) controls transcription of target
genes both directly by interaction with DNA regulatory elements and indirectly by cross-talk …

Eph receptors constitute the largest family of tyrosine kinase receptors and, together with
their plasma-membrane-bound ephrin ligands, have many important functions during …

VARIOUS in vitro studies have suggested that ErbB4 (HER4) is a receptor for the
neuregulins, a family of closely related proteins implicated as regulators of neural and muscle …

Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate axon
guidance and bundling in the developing brain, control cell migration and adhesion, and …

Brain-derived neurotrophic factor (BDNF) and its receptor TrkB regulate both short-term
synaptic functions and long-term potentiation (LTP) of brain synapses, raising the possibility that …

We have generated mice carrying a germline mutation in the tyrosine kinase catalytic
domain of the trkB gene. This mutation eliminates expression of gp145 trkB , a protein-tyrosine …