Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?

…, L Bozzao, E Bluhmki, W Hacke, R von Kummer - Stroke, 2001 - Am Heart Assoc
Background and Purpose—The term symptomatic hemorrhage secondary to ischemic
stroke implies a clear causal relationship between clinical deterioration and hemorrhagic …

[HTML][HTML] Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

…, T Machnig, D Schneider, R Von Kummer… - New England journal …, 2008 - Mass Medical Soc
Background Intravenous thrombolysis with alteplase is the only approved treatment for acute
ischemic stroke, but its efficacy and safety when administered more than 3 hours after the …

[HTML][HTML] Thrombectomy within 8 hours after symptom onset in ischemic stroke

…, M Goyal, AM Demchuk, R von Kummer… - … England Journal of …, 2015 - Mass Medical Soc
Background We aimed to assess the safety and efficacy of thrombectomy for the treatment
of stroke in a trial embedded within a population-based stroke reperfusion registry. Methods …

Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)

W Hacke, M Kaste, C Fieschi, R Von Kummer… - The Lancet, 1998 - thelancet.com
Background Thrombolysis for acute ischaemic stroke has been investigated in several
clinical trials, with variable results. We have assessed the safety and efficacy of intravenous …

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: the European Cooperative Acute Stroke Study (ECASS)

…, M Kaste, C Fieschi, D Toni, E Lesaffre, R Von Kummer… - Jama, 1995 - jamanetwork.com
Objective. —To evaluate the efficacy and safety of intravenous thrombolysis using recombinant
tissue plasminogen activator (rt-PA) in patients with acute ischemic stroke. Design. —…

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

KR Lees, E Bluhmki, R Von Kummer, TG Brott, D Toni… - The Lancet, 2010 - thelancet.com
Background Early administration of intravenous recombinant tissue plasminogen activator (rt-PA)
after ischaemic stroke improves outcome. Previous analysis of combined data from …

[HTML][HTML] Endovascular therapy after intravenous t-PA versus t-PA alone for stroke

…, B Yan, FL Silver, R Von Kummer… - … England Journal of …, 2013 - Mass Medical Soc
Background Endovascular therapy is increasingly used after the administration of intravenous
tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic …

Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the …

V Larrue, R von Kummer, A Müller, E Bluhmki - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Intravenous thrombolysis with recombinant tissue plasminogen
activator (rtPA) improves the outcome for ischemic stroke patients who can be treated within …

'Malignant'middle cerebral artery territory infarction: clinical course and prognostic signs

…, M Spranger, M De Georgia, R von Kummer - Archives of …, 1996 - jamanetwork.com
Background: Although the clinical features of space-occupying ischemic stroke are well
known, there are limited prospective data on the clinical course of complete middle cerebral …

Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement

…, AJ Yoo, P Khatri, TA Tomsick, R Von Kummer… - Stroke, 2013 - Am Heart Assoc
Methods A hybrid approach based on established processes described by Glaser15 and by
the National Institutes of Health (http://prevention. nih. gov/cdp/about. aspx) 16 was used to …