… tomography (r = 0.68, P < 0.001) but only weakly with the amount of subcutaneous fat (r =
0.22, P < 0.05) (Fig. 1E). We also analyzed KKAy mice, a model for obese type II diabetes. …

Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on the
nuclear capture and fission reactions that occur when non-radioactive boron-10, which is a …

There is a rapid global rise in obesity, and the link between obesity and diabetes remains
somewhat obscure. We identified an adipocytokine, designated as visceral adipose tissue-…

White adipocytes are unique in that they contain large unilocular lipid droplets that occupy
most of the cytoplasm. To identify genes involved in the maintenance of mature adipocytes, …

While searching for natural ligands for the peroxisome proliferator-activated receptor (PPAR)
γ, we identified a synthetic compound that binds to this receptor. Bisphenol A diglycidyl …

STAT3 regulates glucose homeostasis by suppressing the expression of gluconeogenic
genes in the liver. The mechanism by which hepatic STAT3 is regulated by nutritional or …

The transcription factor, signal transducer and activator of transcription-3 (STAT-3) contributes
to various physiological processes. Here we show that mice with liver-specific deficiency …

Krüppel-like zinc finger transcription factors (KLFs) play diverse roles during cell
differentiation and development in mammals. We have now shown by microarray analysis that …

Sry (sex-determining region on the Y chromosome) is a master gene that initiates testis
differentiation of the bipotential indifferent gonad in mammals. In mice, Sry expression is …

In order to determine desiccation tolerances of bacterial strains, the survival of 58
diarrheagenic strains (18 salmonellae, 35 Shiga toxin-producing Escherichia coli [STEC], and 5 …