User profiles for R. Nick Bryan

Robert Nick Bryan

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 5269

Effect of intensive vs standard blood pressure control on probable dementia: a randomized clinical trial

JD Williamson, NM Pajewski, AP Auchus, RN Bryan… - Jama, 2019 - jamanetwork.com
Importance There are currently no proven treatments to reduce the risk of mild cognitive
impairment and dementia. Objective To evaluate the effect of intensive blood pressure control on …

Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects

…, JM Links, JL Prince, RN Bryan… - Journal of Cerebral …, 1992 - journals.sagepub.com
Accuracy in in vivo quantitation of brain function with positron emission tomography (PET)
has often been limited by partial volume effects. This limitation becomes prominent in studies …

One-year age changes in MRI brain volumes in older adults

…, S Golski, MA Kraut, EJ Metter, RN Bryan… - Cerebral …, 2000 - academic.oup.com
Longitudinal studies indicate that declines in cognition and memory accelerate after age 70
years. The neuroanatomic and neurophysiologic underpinnings of cognitive change are …

Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy

…, C Truwit, C Davatzikos, RN Bryan - The Lancet …, 2011 - thelancet.com
Background People with type 2 diabetes are at risk of cognitive impairment and brain
atrophy. We aimed to compare the effects on cognitive function and brain volume of intensive …

Sex differences in brain aging: a quantitative magnetic resonance imaging study

…, G Ratcliff, LJ Unitas, B Billig, RN Bryan - Archives of …, 1998 - jamanetwork.com
Background Little is known about the effect of sex on age-related changes in brain structure.
Methods Quantitative magnetic resonance imaging of the brain was performed in 330 …

Magnetic resonance abnormalities and cardiovascular disease in older adults. The Cardiovascular Health Study.

…, JM Gardin, LP Fried, EP Steinberg, RN Bryan - Stroke, 1994 - Am Heart Assoc
Cerebral magnetic resonance imaging often detects abnormalities whose significance is
unknown. The prevalence and correlates of findings such as ventricular enlargement, sulcal …

Association between blood pressure level and the risk of myocardial infarction, stroke, and total mortality: the cardiovascular health study

…, D Levine, DH O'Leary, RN Bryan… - Archives of internal …, 2001 - jamanetwork.com
Background Recent reports have drawn attention to the importance of pulse pressure as a
predictor of cardiovascular events. Pulse pressure is used neither by clinicians nor by …

Diagnosis of acute cerebral infarction: comparison of CT and MR imaging.

RN Bryan, LM Levy, WD Whitlow… - American journal …, 1991 - Am Soc Neuroradiology
The appearance of acute cerebral infarction was evaluated on MR images and CT scans
obtained in 31 patients within 24 hr of the ictus; follow-up examinations were performed 7-10 …

White matter hyperintensity on cranial magnetic resonance imaging: a predictor of stroke

…, WT Longstreth Jr, AM Arnold, C Bernick, RN Bryan… - Stroke, 2004 - Am Heart Assoc
Background and Purpose— We have previously reported that several “silent” infarcts found
on magnetic resonance imaging (MRI) were a risk factor for stroke. Several recent reports …

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

…, J Morris, MS Albert, HJ Grabe, S Resnick, RN Bryan… - Brain, 2020 - academic.oup.com
Deep learning has emerged as a powerful approach to constructing imaging signatures of
normal brain ageing as well as of various neuropathological processes associated with brain …