SARS-COV 2 is recognized to be responsible for a multi-organ syndrome. In most patients,
symptoms are mild. However, in certain subjects, COVID-19 tends to progress more severely. …

There is widespread interest in macrophages as a therapeutic target in cancer. Here, we
demonstrate that trabectedin, a recently approved chemotherapeutic agent, induces rapid …

In the study of carotid arteries, modern techniques of imaging allow to analyze various alterations
beyond simple luminal narrowing, including the morphology of atherosclerotic plaques…

Background Previous studies have suggested that trabectedin (ecteinascidin-743) could have
antitumour activity in soft-tissue sarcoma. We aimed to study the usefulness of trabectedin …

The role of calcium in atherosclerosis is controversial and the relationship between vascular
calcification and plaque vulnerability is not fully understood. Although calcifications are …

Background The purpose of the study was to retrospectively reassess in our institutional
series at a longer follow-up the value of a systematic attempt to carry out wide resections in …

Inflammatory mediators present in the tumor milieu may promote cancer progression and are
considered promising targets of novel biological therapies. We previously reported that the …

The biodiversity of the Santa Maria di Leuca (SML) coral bank is summarized and its
description is updated using data collected by means of underwater video systems, benthic …

Background First described in 1977, myxofibrosarcoma is one of the most common sarcoma
subtypes of the elderly. Until some years ago, myxofibrosarcoma was diagnosed as “myxoid …

Background Among sarcomas, which are rare cancers, many types are exceedingly rare;
however, a definition of ultra‐rare cancers has not been established. The problem of ultra‐rare …