A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

… pastoris display of the prosequence of R. oryzae lipase (ProROL) (Takahashi et al. 1998).
Although the highest lipase activity achieved with this display was lower than that obtained …

Individuals with rheumatoid arthritis frequently have autoantibodies to citrullinated peptides,
suggesting the involvement of the peptidylarginine deiminases citrullinating enzymes (…

We have found a new type of carbon particle produced by the CO 2 laser ablation of carbon
at room temperature without a metal catalyst. The product has a powder form of graphitic …

A new age has begun in the genetics of rheumatoid arthritis (RA), as genome-wide association
studies scanning the human genome have been put into practical use. Among the RA-…

The axon initial segment (AIS) is positioned between the axonal and somato-dendritic
compartments and plays a pivotal role in triggering action potentials (APs) and determining …

… with tumor cellularity for both astrocytic tumors (r = −.77) and meningiomas (r = −.67). …
Tumor cellularity correlated relatively well with ADC for astrocytic tumors (r = –.77 [Fig 8]). Among …

Transcatheter hepatic artery embolization was performed in 120 patients with unresectable
hepatoma. The cumulative one-year survival rate was 44%. In most cases follow-up …

By means of a large-scale, case-control association study using 92,788 gene-based single-nucleotide
polymorphism (SNP) markers, we identified a candidate locus on chromosome …

A benchmark experiment on Pb 208 shows that polarized proton inelastic scattering at very
forward angles including 0 is a powerful tool for high-resolution studies of electric dipole (E 1…