Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

CS Patlak, RG Blasberg… - Journal of Cerebral …, 1983 - journals.sagepub.com
A theoretical model of blood–brain exchange is developed and a procedure is derived that
can be used for graphing multiple-time tissue uptake data and determining whether a …

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations

CS Patlak, RG Blasberg - Journal of Cerebral Blood Flow & …, 1985 - journals.sagepub.com
The method of graphical analysis for the evaluation of sequential data (eg, tissue and blood
concentrations over time) in which the test substance is irreversibly trapped in the system …

[HTML][HTML] Molecular-genetic imaging: current and future perspectives

RG Blasberg, JG Tjuvajev - The Journal of clinical …, 2003 - Am Soc Clin Investig
Blasberg and … Blasberg, Department of Neurology and Radiology, Memorial Sloan-Kettering
Cancer Center, Box 52, 1275 York Avenue, New York, New York 10021, USA… Blasberg et al. …

Multimodality in vivo molecular-genetic imaging

…, V Ponomarev, RG Blasberg - Bioconjugate …, 2004 - ACS Publications
Multimodality imaging is increasingly being used in molecular-genetic studies in small
animals. The coupling of nuclear and optical reporter genes represents the beginning of a far …

Methods for quantifying the transport of drugs across brain barrier systems

JD Fenstermacher, RG Blasberg, CS Patlak - Pharmacology & therapeutics, 1981 - Elsevier
… (19781 and Blasberg and coworkers {1980a,bl for their investigations of blood brain transfer.
All four of these iv approaches are generally employed on rats and rabbits, but larger. more …

[HTML][HTML] Intrathecal chemotherapy: brain tissue profiles after ventriculocisternal perfusion.

RG Blasberg, C Patlak, JD Fenstermacher - 1975 - books.google.com
… This topic has been the subject of two recent reviews (Broder and Rall, 1972;
Fenstermacher and Blasberg, 1974). … AND BLASBERG, R.: Pharmacological …

Transport of α-aminoisobutyric acid across brain capillary and cellular membranes

RG Blasberg, JD Fenstermacher… - Journal of Cerebral …, 1983 - journals.sagepub.com
The transport of α-aminoisobutyric acid (AIB), N-methyl-AIB (MeAIB), and
diethylenetriaminepentaacetic acid (DTPA) from blood to brain was measured over different …

Imaging the Expression of Transfected Genes in Vivo

…, H Uehara, K Watanabe, B Gansbacher, RG Blasberg - Cancer research, 1995 - AACR
… Tjuvajev, JG, Macapinlac, HA, Daghighian, F., Scott, AM, ginos, JZ, Finn, RD, Kothari, P.,
Desai, R., Zhang, Z., Beauie, B., Graham, M., Larson, S., and Blasberg, RG Imaging of brain …

Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to [18F]Cyclofoxy and Positron Emission Tomography

…, MA Channing, RG Blasberg… - Journal of Cerebral …, 1993 - journals.sagepub.com
Positron emission tomography studies with the opiate antagonist [ 18 F]cyclofoxy ([ 18 F]CF)
were performed in baboons. Bolus injection studies demonstrated initial uptake dependent …

Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression

…, H Thaler, PS Conti, RG Blasberg - Journal of Nuclear …, 2002 - Soc Nuclear Med
The efficacy of 3 radiolabeled probes of current interest for imaging herpes simplex virus
type 1 thymidine kinase (HSV1-tk) expression in vivo with PET, including 124 I- or 131 I-labeled …